SGLT inhibitors have changed the treatment landscape for cardiovascular and kidney disease, particularly in people with type 2 diabetes, heart failure, and chronic kidney disease. That success raises an obvious question: why are SGLT inhibitors in type 1 diabetes still largely outside routine clinical practice? The answer is not a …
Read More »A1C Has a Blind Spot: Could Glycated Albumin Help Clinicians Act Faster?
A1C is one of the most useful tools in diabetes care, but it has an important limitation: it takes time to reflect change. Could a faster-moving marker help clinicians know sooner whether treatment is working? New randomized research on glycated albumin in diabetes offers an intriguing answer. Glycated albumin reflects …
Read More »Human vs. Analogue Insulin: Does Newer Really Mean Better for Type 1 Diabetes?
The choice of human vs analogue insulin is especially important for people with Type 1 diabetes who live where healthcare resources are limited. Analogue insulins are often preferred because their action can be more predictable and flexible. However, human insulin is generally less expensive and may be easier for health …
Read More »The Treatment Stopped—Did the Benefit Last? New Baricitinib Data in Type 1 Diabetes
New follow-up research on baricitinib for type 1 diabetes addresses a crucial question: what happens after the drug is stopped? The original BANDIT trial showed that 48 weeks of oral baricitinib helped preserve beta-cell function in people with recently diagnosed type 1 diabetes. However, new follow-up research examines participants through …
Read More »Two Shots a Year for Hypertension? How RNA Silencing Could Transform Cardiometabolic Care
Poor medication persistence remains one of the hardest barriers to long-term blood pressure control. For people with diabetes, the stakes are especially high because hypertension adds to cardiovascular and kidney risk. Now, research into RNAi for hypertension in people with diabetes is raising an intriguing possibility: could an injection given …
Read More »The Return of Aldose Reductase Inhibitors: Could an Old Idea Finally Pay Off?
Diabetes care has advanced dramatically over the past decade. While therapies such as GLP-1 receptor agonists and SGLT2 inhibitors have transformed glucose management and cardiovascular outcomes, many patients continue to develop long-term complications. Could an older therapeutic target finally provide the missing piece? Interest in aldose reductase inhibitors for diabetes …
Read More »Why Scientists Are Taking Another Look at the BCG Vaccine for Type 1 Diabetes
For more than 100 years, the Bacillus Calmette-Guérin (BCG) vaccine has been used worldwide to help prevent tuberculosis. However, researchers are now exploring another possible role for this familiar vaccine. Recent studies suggest that the BCG vaccine may play a role in treating type 1 diabetes by modifying the immune …
Read More »Why Cardiologists Are Looking Beyond Traditional SGLT2 Therapy
The treatment landscape for type 2 diabetes has changed dramatically over the past decade. While selective SGLT2 inhibitors have become a cornerstone of diabetes management because of their proven cardiovascular and kidney benefits, researchers are now exploring the added potential of dual SGLT1/2 inhibitor therapy for people with diabetes. By …
Read More »Farxiga Just Went Generic—Will Lower Prices Finally Change Diabetes Care?
For many people living with type 2 diabetes, the biggest challenge is not finding an effective medication. It is being able to afford it. That reality may begin to change now that the U.S. Food and Drug Administration (FDA) has approved the first generic versions of Farxiga (dapagliflozin), potentially making …
Read More »Teaching Muscles to Make Insulin: Could Gene Therapy Rewrite the Future of Type 1 Diabetes?
For more than a century, insulin therapy has remained the cornerstone of treatment for type 1 diabetes. While continuous glucose monitors, insulin pumps, and automated insulin delivery systems have dramatically improved diabetes management, they still do not replace the body’s natural ability to regulate blood sugar. As a result, researchers …
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