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Tag Archives: beta-cell preservation

The Treatment Stopped—Did the Benefit Last? New Baricitinib Data in Type 1 Diabetes

Baricitinib type 1 diabetes research concept showing beta-cell preservation and follow-up after treatment ends.

New follow-up research on baricitinib for type 1 diabetes addresses a crucial question: what happens after the drug is stopped? The original BANDIT trial showed that 48 weeks of oral baricitinib helped preserve beta-cell function in people with recently diagnosed type 1 diabetes. However, new follow-up research examines participants through …

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The Honeymoon Phase Won’t Last Forever: Are We Doing Enough to Preserve Beta Cells?

Hourglass beside a healthy pancreas illustration with insulin syringe and glucose meter representing beta-cell preservation during the type 1 diabetes honeymoon phase.

Receiving a diagnosis of type 1 diabetes can feel overwhelming. Yet for many adults, the weeks or months that follow bring an unexpected twist. Blood glucose levels often become easier to control, insulin needs decrease, and some people wonder if their diabetes is actually improving. This temporary period is known …

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The Future of Type 1 Screening: Will Genetics Replace Autoantibodies?

Pediatric genetic screening for type 1 diabetes showing a DNA helix, blood sample, and clinical risk assessment used for early detection of disease risk.

Population-based screening for type 1 diabetes is entering a new era. While autoantibody testing remains the gold standard for identifying individuals at high risk, researchers are increasingly investigating whether type 1 diabetes genetic screening could identify susceptible people even earlier. Advances in genomic science now make it possible to estimate …

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The First Disease-Modifying Treatment After a Type 1 Diabetes Diagnosis: Why Teplizumab Is Changing the Conversation

Pediatric endocrinologist discussing teplizumab treatment options with a family following a new type 1 diabetes diagnosis.

For decades, treatment after a type 1 diabetes diagnosis focused almost entirely on insulin replacement and blood glucose management. While advances in technology have improved care, clinicians have had few ways to address the autoimmune process driving beta-cell loss. That is beginning to change. With the FDA’s expansion of teplizumab-mzwv …

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Delaying Type 1 Diabetes Progression: What Long-Term Data Mean for Screening and Intervention

Immunotherapy vial with diabetes monitoring tools illustrating type 1 diabetes prevention and early intervention research

Can a chronic condition like type 1 diabetes be slowed before it fully develops? Recent long-term studies suggest that preventing or delaying type 1 diabetes may be closer to reality than once believed. In fact, emerging immunotherapy data is changing how clinicians view early-stage disease and the opportunity to intervene …

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GLP-1 Drugs and Beta-Cell Preservation: Can Early Treatment Slow Diabetes Progression?

Medical illustration of pancreas highlighting GLP-1 beta cell function with injection therapy and diabetes treatment elements

Type 2 diabetes often feels like a slow-burning fire that gradually damages the body over time. But what if early intervention could help control that fire before it spreads? Research into how GLP-1 therapies support beta-cell function suggests these treatments may do more than lower blood sugar. They may also …

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Catching Type 1 Earlier: How Autoantibody Screening Is Changing the Playbook

Conceptual image showing type 1 diabetes autoantibody screening with glucose monitor, test tube, pancreas model, and antibody vials labeled GADA, IA-2A, and ZnT8A.

Type 1 diabetes doesn’t have to be a surprise. Thanks to type 1 diabetes autoantibody screening, clinicians can now identify individuals at high risk before symptoms even appear. This early detection opens doors for proactive monitoring, patient education, and potentially delaying or preventing full-blown disease. But who should be screened? …

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Reimagining Remission: Can Short‑Term Intensive Therapy Reset Type 2 Diabetes?

A diabetes management setup featuring a glucose meter, vegetables, apple, insulin pen, and a notepad labeled "Intensive Therapy"

Could the conventional “lifelong treatment” model for type 2 diabetes be rethought? Recent trials suggest that short‑term intensive therapy may offer more than transient glycemic control—it might trigger lasting remission in newly diagnosed patients. Such interventions, combining aggressive pharmacologic therapy or insulin with lifestyle change, show potential to preserve β‑cell …

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