Specialties

Evidence suggests that the timing of diabetes onset and exposure to serious hypoglycemia may be factors in the cognitive decline of type 1 diabetics… The new study is the first of its kind to follow intelligence quotient (IQ) in type 1 diabetes patients from diagnosis in childhood into young adulthood …

In this week’s Homerun Slides, we cover the importance of the Incretin Effect with an examination of the mechanisms of action of GLP-1 agonist and DPP-4 inhibitor drugs including the cardioprotective aspects of these medications…. To download these slides in PowerPoint (.ppt) format, use this link: Diabetes Mellitus 101 for Cardiologists, Part 11 …

An HbA1c of 6.5-6.9% at 26 weeks’ gestation correlated with significantly elevated risk of preterm delivery, preeclampsia, need for neonatal glucose infusion, and a composite adverse outcome… Michael J.A. Maresh, M.D., from St. Mary’s Hospital in Manchester, U.K., and colleagues conducted a prospective assessment involving 725 women with type 1 …

Increased breath acetone was linked to increases in beta hydroxybutyrate (a ketone) levels in the blood… Researchers may have identified a chemical marker for type 1 diabetes in the breath of children. Around 1 in 4 children with type 1 diabetes are unaware they have a condition until they develop …

High glucose, obesity studied for possible link to cancer development… The findings highlight the importance of screening for carcinomas in patients with diabetes to aid early detection and reduce premature mortality, say the researchers. The Australian researchers found that the highest excess risks were observed for cancers of the pancreas, …

Mortality, cardiovascular disease risk remains same for patient with secondary hyperparathyroidism… After further review, adjusted findings from the EVOLVE Trial showed that cinacalcet may reduce the risk of fracture among patients on dialysis. In a pre-specified subgroup analysis, cinacalcet was associated with reduced fracture risk after taking baseline characteristics and …

Scans may be documenting early development of food reward circuitry in young children… A study suggests that children who are obese may overeat because they crave more sugar than slimmer youngsters. Brain scans showed that their reward centers are stimulated more intensely when they are exposed to sweet flavors. Scientists …

In this week’s Homerun Slides, we continue with our review of diabetes therapy from a cardiovascular perspective. We finish up our discussion of how to treat inflammation issues and move on to treating the whole biome including a look at probiotic, prebiotic, and antibiotic treatment of the abnormal gut biome…. To download …

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Disordered gastrointestinal motor function occurs in both type 1 and type 2 diabetes and can result in symptoms of nausea, vomiting, diarrhea or constipation, malnutrition, poor glycemic control and delayed absorption of orally administered drugs (Figure 23.1). Gustatory sweating, typically affecting the …

Higher A1C target recommended for patients over 65 with comorbidities… A team of Canadian and American researchers have analyzed data from the ACCORD trial to investigate whether the intensive lowering of glucose concentrations affects the risk of ischemic heart disease in patients with type 2 diabetes. The researchers assessed 10,251 …