Risk found unaffected by prolonged exposure to pioglitazone… According to a recent study of more than one million people published in Diabetologia, the diabetes medications pioglitazone (Actos) and rosiglitazone (Avandia) do not appear to have an association with bladder cancer. It is known that bladder tumors overexpress transcription factor called …
Read More »Aaron Vinik, MD, Q5: New Devices to Detect Neuropathy
Dr. Aaron Vinik discusses a very simple and quick device that can effectively detect neuropathy but also comments that it’s success is tied in to many other factors….
Read More »Diabetes Mellitus 101 for Cardiologists, Part 9
In this week’s Homerun Slides, Dr. Stanley Schwartz continues his review of pioglitazone as a therapy for both diabetes and cardiovascular issues. He shows how this medication is cardioprotective and that patients on this plus metformin do much better after hospitalization…. To download these slides in PowerPoint (.ppt) format, use this link: Diabetes …
Read More »Niacin Benefits Kidney Mortality
The proportion of patients experiencing a rapid decline in estimated glomerular filtration rate (eGFR) can be decreased significantly with niacin, as can all-cause mortality… Elani Streja, PhD Chief investigator, University of California, Irvine Medical Center, commented on the study, stated, “Across all models of adjustment, patients who took niacin had …
Read More »Kidney Function Found to be Affected by Perceived Racial Discrimination
According to a new study, perceived racial discrimination may contribute to disparities in rates of decline… Psychosocial factors such as perceived racial discrimination have been associated with chronic diseases, but little is known about the relationship between perceived racial discrimination and kidney function decline. Researchers led by Angedith Poggi-Burke, MPH …
Read More »Diabetes Mellitus 101 for Cardiologists, Part 8
In this week’s Homerun Slides, Dr. Stanley Schwartz reviews pioglitazone as a therapy for both diabetes and cardiovascular issues. Topics include: Pioglitazone in Dysmetabolic Syndrome, Prediabetes, Type 2 Diabetes; Effect of Pioglitazone on Cardiac Mass and Function: and Glitazones (including rosiglitazone) and Cardiac Function…. To download these slides in PowerPoint (.ppt) format, …
Read More »Handbook of Diabetes, 4th Ed., Excerpt #20: Foot Problems in Diabetes
Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP The high-risk diabetic foot The lifetime risk of a person with diabetes developing foot ulceration is around 25%. Recent studies suggest that the population-based incidence of diabetic foot ulcers is 1-4% with a prevalence of 4-10%. The risk of amputation is 10–30-fold …
Read More »Fertility Reduced in Individuals with Childhood-Onset Type 1 Diabetes
Offspring count higher for unaffected siblings, adult-onset type 1 patients…. The Finnish researchers assessed fertility, defined as number of offspring, in the affected and unaffected siblings included in the T1DGC. Clinical information was collected from participants aged ≥18 years at the time of examination. The number of offspring of affected …
Read More »Excess Mortality from Cardiovascular Causes in Type 1 Diabetes
Degree of glycemic control is investigated for excess risk of death due to cardiovascular cause…. When compared to the general population, patients with type 1 diabetes are at increased risk of premature death. The most common cause of death is cardiovascular disease in patients over thirty years of age. Adequate …
Read More »Rates of Diabetic Kidney Disease May be More Common than We Thought
New study says autopsy reports show nearly 50% of diabetes patients had diabetic nephropathy…
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