Specialties

Mortality, cardiovascular disease risk remains same for patient with secondary hyperparathyroidism… After further review, adjusted findings from the EVOLVE Trial showed that cinacalcet may reduce the risk of fracture among patients on dialysis. In a pre-specified subgroup analysis, cinacalcet was associated with reduced fracture risk after taking baseline characteristics and …

Scans may be documenting early development of food reward circuitry in young children… A study suggests that children who are obese may overeat because they crave more sugar than slimmer youngsters. Brain scans showed that their reward centers are stimulated more intensely when they are exposed to sweet flavors. Scientists …

In this week’s Homerun Slides, we continue with our review of diabetes therapy from a cardiovascular perspective. We finish up our discussion of how to treat inflammation issues and move on to treating the whole biome including a look at probiotic, prebiotic, and antibiotic treatment of the abnormal gut biome…. To download …

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Disordered gastrointestinal motor function occurs in both type 1 and type 2 diabetes and can result in symptoms of nausea, vomiting, diarrhea or constipation, malnutrition, poor glycemic control and delayed absorption of orally administered drugs (Figure 23.1). Gustatory sweating, typically affecting the …

Higher A1C target recommended for patients over 65 with comorbidities… A team of Canadian and American researchers have analyzed data from the ACCORD trial to investigate whether the intensive lowering of glucose concentrations affects the risk of ischemic heart disease in patients with type 2 diabetes. The researchers assessed 10,251 …

Risk found unaffected by prolonged exposure to pioglitazone… According to a recent study of more than one million people published in Diabetologia, the diabetes medications pioglitazone (Actos) and rosiglitazone (Avandia) do not appear to have an association with bladder cancer. It is known that bladder tumors overexpress transcription factor called …

Dr. Aaron Vinik discusses a very simple and quick device that can effectively detect neuropathy but also comments that it’s success is tied in to many other factors….

In this week’s Homerun Slides, Dr. Stanley Schwartz continues his review of pioglitazone as a therapy for both diabetes and cardiovascular issues. He shows how this medication is cardioprotective and that patients on this plus metformin do much better after hospitalization…. To download these slides in PowerPoint (.ppt) format, use this link: Diabetes …

The proportion of patients experiencing a rapid decline in estimated glomerular filtration rate (eGFR) can be decreased significantly with niacin, as can all-cause mortality… Elani Streja, PhD Chief investigator, University of California, Irvine Medical Center, commented on the study, stated, “Across all models of adjustment, patients who took niacin had …

According to a new study, perceived racial discrimination may contribute to disparities in rates of decline… Psychosocial factors such as perceived racial discrimination have been associated with chronic diseases, but little is known about the relationship between perceived racial discrimination and kidney function decline. Researchers led by Angedith Poggi-Burke, MPH …