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Practical Diabetes Care, 3rd Ed., Excerpt #9: Infections in Diabetes Part 1 of 3

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David Levy, MD, FRCP Introduction Infections in patients with diabetes are a persistent trap for both the inexperienced and world-wise physician. Whenever someone with diabetes presents unwell, always consider the possibility of infection. High blood glucose levels predispose to some acute infections, especially postoperatively, but other mechanisms are involved, for example …

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GLP-1 Not As Effective after Roux-en-Y Gastric Bypass

Researchers compared glucose and hormonal responses to a liquid meal test in 20 obese participants with T2 who underwent RYGB or nonsurgical intensive lifestyle modification… Rapid glycemic improvements following Roux-en-Y gastric bypass (RYGB) are frequently attributed to the enhanced GLP-1 response, but causality remains unclear. To determine the role of …

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Effects of Lifestyle Intervention and Metformin on the Development of Type 2 in Women With or Without GDM

Women with a history of GDM had 48% increased risk of developing diabetes… From previous studies it is known that women with gestational diabetes are at a higher risk for the development of type 2 diabetes. Previous results from the Diabetes Prevention Program (DPP) showed that Intensive Lifestyle Intervention (ILS) …

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Diabetes Screening at the Dentist

Dental visits may allow for diabetes screening and monitoring glucose control in at-risk patients… A new study suggests that using gingival crevicular blood, collected during dental visits, for HbA1c testing produced values that were nearly identical to those obtained using finger stick blood. Correlation was 0.991 between the HbA1c values …

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Does Detemir Cross the Placenta in Women with Diabetes?

The relatively new long-acting insulin analog needs to be studied to determine its absorption pharmacokinetics… Insulin detemir (IDet) is a relatively new long-acting insulin analog that offers improved absorption pharmacokinetics and slower tissue distribution due to high plasma protein binding. As IDet is increasingly used for treatment of insulin-requiring diabetes, …

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