David Levy, MD, FRCP Introduction Infections in patients with diabetes are a persistent trap for both the inexperienced and world-wise physician. Whenever someone with diabetes presents unwell, always consider the possibility of infection. High blood glucose levels predispose to some acute infections, especially postoperatively, but other mechanisms are involved, for example …
Read More »Peter Katzmarzyk, PhD, Q5: Increase in Childhood Obesity Leading to More Type 2 Adults
Peter Katzmarzyk, PhD, discusses the growing problem of childhood obesity which frequently contributes to the earlier development of adult type 2 diabetes. He also mentions that, particularly in the southern U.S., there are more and more incidences of type 2 in children and teens being reported. More videos with Dr. …
Read More »A Closer Look at Diabetic Peripheral Neuropathy and Daily Activities
Diabetic peripheral neuropathy can have an effect on balance… Previous studies show that patients with diabetic peripheral neuropathy (DPN) have an altered gait strategy and a fivefold increased risk of falling. Falling is a major health risk, especially with disease progression and in the elderly. Diabetic patients with peripheral neuropathy …
Read More »Abdominal Muscle and Type 2 Diabetes in Postmenopausal Women
A greater muscle to total abdominal area ratio was associated with lower odds of diabetes…. Skeletal muscle loss with diabetes onset is common and low muscle mass can be a potential risk factor for diabetes. Studies show that glucose storage and consumption by lean muscle are important factors when looking …
Read More »GLP-1 Not As Effective after Roux-en-Y Gastric Bypass
Researchers compared glucose and hormonal responses to a liquid meal test in 20 obese participants with T2 who underwent RYGB or nonsurgical intensive lifestyle modification… Rapid glycemic improvements following Roux-en-Y gastric bypass (RYGB) are frequently attributed to the enhanced GLP-1 response, but causality remains unclear. To determine the role of …
Read More »Effects of Lifestyle Intervention and Metformin on the Development of Type 2 in Women With or Without GDM
Women with a history of GDM had 48% increased risk of developing diabetes… From previous studies it is known that women with gestational diabetes are at a higher risk for the development of type 2 diabetes. Previous results from the Diabetes Prevention Program (DPP) showed that Intensive Lifestyle Intervention (ILS) …
Read More »Diabetes Screening at the Dentist
Dental visits may allow for diabetes screening and monitoring glucose control in at-risk patients… A new study suggests that using gingival crevicular blood, collected during dental visits, for HbA1c testing produced values that were nearly identical to those obtained using finger stick blood. Correlation was 0.991 between the HbA1c values …
Read More »Women’s Risk For Diabetes Increases If Parents Smoked
Women whose mothers smoked while pregnant are two to three times as likely to be diabetic as adults…. Fathers who smoked while their daughter was in utero also contribute to an increased diabetes risk, but more research is needed to establish the true effect. Michele La Merrill, assistant professor of …
Read More »Increased Cancer Risk Associated with Type 1 and Type 2 Diabetes
Why is cancer risk higher among diabetes patients?… Evidence indicates an increased risk of certain cancers among people with type 2 diabetes. Evidence for rarer cancers and for type 1 diabetes is limited. Australian researchers recently explored the excess risk of site-specific cancer incidence and mortality among people with type …
Read More »Does Detemir Cross the Placenta in Women with Diabetes?
The relatively new long-acting insulin analog needs to be studied to determine its absorption pharmacokinetics… Insulin detemir (IDet) is a relatively new long-acting insulin analog that offers improved absorption pharmacokinetics and slower tissue distribution due to high plasma protein binding. As IDet is increasingly used for treatment of insulin-requiring diabetes, …
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