Gastroenterology

Researchers compared glucose and hormonal responses to a liquid meal test in 20 obese participants with T2 who underwent RYGB or nonsurgical intensive lifestyle modification… Rapid glycemic improvements following Roux-en-Y gastric bypass (RYGB) are frequently attributed to the enhanced GLP-1 response, but causality remains unclear. To determine the role of …

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Disordered gastrointestinal motor function occurs in both type 1 and type 2 diabetes and can result in symptoms of nausea, vomiting, diarrhea or constipation, malnutrition, poor glycemic control and delayed absorption of orally administered drugs (Figure 23.1). Gustatory sweating, typically affecting the …

  Gastric bypass surgery shows better outcomes for long-term weight loss, controlling type 2 diabetes, hypertension, and cholesterol level…. Puzziferri and colleagues conducted a clinical review of 29 studies (7,971 patients) looking at outcomes of gastric bypass, gastric band or sleeve gastrectomy on patients with BMI ≥35 at 1 year …

According to research done in the SLIMM-T2D randomized trial, gastric bypass surgery may have additional benefits for patients with diabetes and obesity…. 

In a phase 2 trial, patients with diabetic gastroparesis displayed increased gastric emptying and improvement in vomiting after treatment with relamorelin-131…. 

Possible circumvention for anti-nausea drug, metoclopramide, shows promise….  

Differing responses to GLP-1 post-surgery show different rates of metabolic improvement…. 

‘Reprogrammed’ glucose uptake in the small intestine may explain why gastric bypass surgery can sometimes result in the early resolution of type 2 diabetes…. 

Researchers looked at the change in hormones and amino acid levels following gastric bypass surgery…. 

In a small study, diabetes patients with gastroparesis experienced significant relief of nausea when using needleless acupuncture….