Drinking grapefruit juice daily can lead to weight loss and help control blood glucose… Grapefruit juice is considered to be high in nutrients while remaining relatively low in calories when compared to other fruit juices. These diets often rely on daily low calorie commitment, which calls into question the true …
Read More »Light Technology May Be Used to Control Type 2 Diabetes
Use of blue LED light activates sulfonylureas… The use of sulfonylureas has long been an option for controlling type 2 diabetes. Their use is often associated with hypoglycemia and weight gain. A new technology seeks to minimize these side effects. Researchers are looking at a prototype sulfonylurea, JB253, which stimulates …
Read More »Blocking a Genetic Variant Associated with Type 2 Diabetes May Improve Insulin Secretion
Yohimbine, a α2A-adrenergic receptor agonist, showed a 29% increase in insulin secretion in patients with type 2 diabetes related to the genetic variation… The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type …
Read More »The Role of Glutamine in Human Carbohydrate Metabolism in Kidney and Other Tissues
Glutamine is the most abundant amino acid in the human body and is involved in more metabolic processes than any other amino acid. Recent studies using isotopic and balance techniques have greatly advanced the understanding of glutamine metabolism in humans and its role in glucose metabolism in the kidney and other …
Read More »Diabetes Mellitus 101 for Cardiologists, Part 2
In this week’s Homerun Slides, courtesy Dr. Stanley Schwartz, we continue our examination of diabetes from a cardiologist’s perspective with topics including the Factors Contributing to Cardiometabolic Risk and the Pathophysiology of Diabetic Complications: Implications for Goals of Therapy…. To download the complete set of these slides in PowerPoint (.ppt) …
Read More »Handbook of Diabetes, 4th Ed., Excerpt #14: Diabetic Eye Disease
Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Diabetic eye disease primarily affects the retinal vasculature, but the iris and lens can also be involved. Most people with diabetes will show signs of retinopathy after 25 years duration, but only a minority progress to the severest form. Photocoagulation has revolutionized …
Read More »LifeVac
LifeVac The LifeVac is a non-powered single patient portable suction apparatus developed for resuscitating a choking victim when standard ACLS protocol has been followed without success. The LifeVac comes with two mask sizes, medium and large.
Read More »For Your Patients – Why Daily Movement Improves Your Brain Health (Part 2): Brain Hormone Changes
by Dr. Sheri Colberg, Ph.D., FACSM Continuing from my last column, here are additional reasons why your brain needs for you to be active related to changes in your brain hormones. Your brain can’t afford for you to be sedentary, at least not if you want to live long and …
Read More »Vitamin D and Type 2 Diabetes Risk
In an analysis using genetic data from over 25 different studies involving diabetes patients, researchers can find no causal association between higher vitamin D levels and lower diabetes risk… Low circulating concentrations of 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, have been associated with an increased risk of …
Read More »Could a Lower Dose of Otelixizumab Preserve Beta-cell Function in Type 1?
Previous studies used higher doses of otelixizumab, an anti-CD3 monoclonal antibody, but also saw a reactivation of the Epstein Barr virus…. In patients with type 1 diabetes, a higher C-peptide concentration is associated with a controlled HbA1c and fewer complications. Otelixizumab is an anti-CD3 monoclonal antibody that works by …
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