Single-tablet approach hoped to boost treatment compliance and help patients better manage condition.. Synjardy contains empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin, a biguanide. It is not for the treatment of type 1 diabetes or diabetic ketoacidosis. The drug label contains a boxed warning on the risk of …
Read More »FDA Warns DPP-4 Inhibitors Could Cause Severe and Disabling Joint Pain
Risk warning, precaution added to labels of all drugs in this class… FDA warned recently that DPP-4 inhibitors could cause severe and disabling joint pain. The agency has added a new warning and precaution about this risk to the labels of all drugs in this class. If patients experience …
Read More »Diabetic Foot Ulcers Linked to Premature Death
Study cites vascular, nonvascular causes…. The purpose of this study was to assess the odds of all-cause mortality in individuals with diabetic foot ulceration (DFU) compared with those with diabetes and no history of DFU. In addition, we sought to determine the strength of association of DFU with cardiovascular and …
Read More »A1c Levels & CV Events Modestly Related in Type 2 Diabetes
Researchers seek link between glycemic control and new CV events and mortality… The findings, based on 1,687 adults, also revealed about a 16% increased risk for all-cause mortality with every 1% increase in A1C levels among diabetes patients with and without vascular disease. There was no difference in relationship among …
Read More »Diabetes and Fatty Liver Associated with Further Liver Problems
Adding liver fibrosis to the long list of diabetic complications under consideration… A recent study published in Hepatology evaluated various risk factors for liver fibrosis in a Dutch population. The call for concern is the prevalence of liver fibrosis in a patient population with low prevalence of hepatitis—the usual suspect …
Read More »The Debate about Diabetes’ Effects on the Diaphragm Continues
New study suggests respiratory research in diabetes patients needs to be done differently in future… Diabetes has been known to cause respiratory problems in patients. Often aerobic and endurance training is encouraged to counteract this issue. Current respiratory research in diabetes patients has focused on diaphragm muscles and other skeletal …
Read More »Potential, Prediabetes Genetic Marker Discovered
Research pinpoints molecular link between insulin resistance and mitochondrial changes… A recent study published in Clinical Epigenetics said researchers sought to discover if they could find any biomarkers in a group of patients with no pre-existent diabetes or cardiovascular disease, but indication of prediabetes and insulin resistance. Researchers analyzed data …
Read More »Effects of Diabetes Medications on Heart Complications
Reduced risk of heart attacks, strokes, cardiovascular events suggested.
Read More »Effects of Glycemic Control on Renal Complications
Researchers study antidiabetic treatments, other factors associated with control… There are two main kidney diseases that are correlated with type 2 diabetes, which are chronic kidney disease and diabetes nephropathy. Good glycemic control can interrupt the progression of kidney diseases in type 2 diabetes patients with renal problems. Currently, the …
Read More »Impact of Gastric Bypass Surgery on Post-Challenge Serum Glucose Levels
New evidence suggests surgery has glucose benefits beyond weight reduction effects… A decrease in blood sugar values after gastric bypass surgery is associated with weight reduction. In addition to that, evidence suggests that gastric bypass surgery has affected glucose metabolism as well. The Morbid Obesity treatment, Bariatric surgery versus Intensive …
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