Diabetes

Most people think diabetes-related blood vessel damage begins only after years of high blood sugar. However, scientists are uncovering evidence that injury may start much earlier, in a structure so thin it cannot be seen during a routine medical exam. This microscopic layer, known as the endothelial glycocalyx, acts as …

New research is changing the conversation around protein and metabolic health. For years, high-protein diets have been praised for supporting weight loss, preserving muscle, and improving blood sugar control. However, scientists are now discovering that the story may be more complex. Rather than blaming protein itself, researchers are focusing on …

When a person develops diabetes at a young age, is not overweight, and has several family members with the condition, is it really type 2 diabetes? In many cases, the answer may be no. A growing body of evidence suggests that thousands of people worldwide are living with HNF1A-MODY, a …

The transition from pediatric to adult diabetes care is one of the most challenging periods in the lives of young people with diabetes. While many adolescents successfully manage their condition with the support of pediatric diabetes teams, moving into adult healthcare often coincides with worsening blood glucose control, missed appointments, …

For years, diabetic kidney disease (DKD) has been viewed as a single condition that progresses in a fairly predictable way. However, new research suggests that this assumption may overlook important biological differences between patients. Scientists have now identified a previously hidden subtype of diabetic kidney disease marked by increased B-cell …

People with diabetes often focus on blood sugar, A1C, and cholesterol. However, very high triglyceride levels deserve just as much attention because they can trigger acute pancreatitis, a painful and potentially life-threatening condition. The connection between diabetes, high triglycerides, and pancreatitis is especially important because severe hypertriglyceridemia can develop silently …

For many people with diabetes, lowering LDL cholesterol is just as important as controlling blood sugar. However, not everyone reaches their cholesterol goals with statins alone, and injectable PCSK9 inhibitors can be inconvenient or intimidating. Now, a new option has arrived. The FDA has approved the first oral PCSK9 inhibitor, …

Night-shift work keeps hospitals, factories, transportation systems, and emergency services running around the clock. However, while society benefits from overnight workers, their metabolic health often pays the price. Recent continuous glucose monitoring (CGM) studies have shown that shift work is strongly associated with greater glycemic variability in people with diabetes, …

Finding the right diabetes medication often involves trial and error. One patient may respond well to a GLP-1 receptor agonist, while another sees little benefit from the same treatment. As a result, clinicians frequently adjust medications before finding the most effective option. What if doctors could test a patient’s response …

Every new diabetes medication must prove it is both safe and effective before reaching patients. Traditionally, that process depends on large clinical trials that require thousands of volunteers, years of follow-up, and significant financial investment. However, what if researchers could reduce the number of participants while still producing reliable scientific …