Type 1 Diabetes

Why is cancer risk higher among diabetes patients?… Evidence indicates an increased risk of certain cancers among people with type 2 diabetes. Evidence for rarer cancers and for type 1 diabetes is limited. Australian researchers recently explored the excess risk of site-specific cancer incidence and mortality among people with type …

Optimum HbA1c level yet to be determined… HbA1c is strongly related to the development of diabetes complications, but it is still controversial as to which HbA1c level to strive for in the treatment of type 1 diabetes. Swedish researchers evaluated HbA1c, followed from diagnosis, as a predictor of severe microvascular …

However, advancement in medications and better controlled regimens may be contributing to a decline in psychiatric disorders among this population… We know from previous studies and research that there is a increased risk and prevalence for depression in the diabetic population. Other trials have also linked diabetes with different subtypes …

Glucose-dependent insulinotropic polypeptide and glucagon- like peptide-1 have glucose-dependent effects on glucagon secretion but differ in their effects on type 1 and type 2 diabetes patients… From various studies we know that glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have glucose-dependent effects on glucagon secretion. GIP causes increased glucagon …

In the meta-analysis, women also had twice the excess risk of fatal and nonfatal vascular events, compared with men with type 1 diabetes… Australian researchers have done a meta-analysis to provide reliable estimates of any sex differences in the effect of type 1 diabetes on risk of all-cause mortality and …

Most with long-term diagnosis foud to continue to secrete low levels of insulin… In a large-population based study, researchers used sensitive C-peptide assays to demonstrate that 43-74% people with longstanding (>5 years) type 1 diabetes are microsecretors of endogenous insulin with C-peptide levels. The Scottish researchers measured the occurrence of …

Corneal confocal microscopy (CCM) can predict incipient peripheral neuropathy in patients with type 1 diabetes… The technique involves the examination of unmyelinated nerve fibers at high magnification using a laser-scanning corneal confocal microscope to image the subbasal nerve plexus of the patient’s cornea. Increased severity of diabetic peripheral neuropathy is …

Janelle, an RN, is 36 years old with type 1 diabetes. She has a busy life between family and work. She eats healthy, exercises regularly, and wears a pump but occasionally has severe hypoglycemia, especially during exercise and at night. When I met her, I recommended she wear a continuous …

Glargine 300 more effective than glargine 100 currently available… Two single-dose studies were conducted in Japan and Europe to compare the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of new insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) in people with type 1 diabetes mellitus. In two double-blind, randomized, crossover …

Insulin resistance with increasing LDL cholesterol were related to low peak volume of oxygen level… Diabetic nephropathy and cardiovascular disease are strongly related in adults with type 1 diabetes, yet little is known about this relationship in adolescents prior to the onset of detectable clinical disease. The researchers hypothesized that …