Type 1 Diabetes

A previous history of severe hypoglycemia is linked to increased death rates after a cardiovascular event in type 1 diabetes patients… Hypoglycemia is the most common and life-threatening complication of type 1 diabetes. The average type diabetes patient experiences about two episodes of hypoglycemia per week. Patients with type 1 …

Delayed diagnosis leading to high instances of DKA in children… Type 1 is the most common form of diabetes in diagnosed children and adolescents. In 2009, the CDC reported the prevalence at 1.93 in every 1,000 children and adolescents, whereas type 2 diabetes affects 0.24 in every 1,000. In a …

Physical activity intervention had a positive impact on reducing HbA1c, BMI and total cholesterol but insulin dosage did not change in the study… Due to the increased risk of cardiovascular disease in type 1 diabetes patients, physical activity is advised. This recommendation is used in combination with insulin therapy and …

A new study found enterovirus infection increased the risk of type 1 diabetes in children… Doctors in Taiwan have found evidence that links enterovirus infection or EV (poliovirus, Coxsackievirus A and B, echovirus) and type 1 diabetes in children. Previous studies have shown an association between EV infection and type …

Previous studies used higher doses of otelixizumab, an anti-CD3 monoclonal antibody, but also saw a reactivation of the Epstein Barr virus….   In patients with type 1 diabetes, a higher C-peptide concentration is associated with a controlled HbA1c and fewer complications. Otelixizumab is an anti-CD3 monoclonal antibody that works by …

  Maternal weight gain is key to controlling infant birth weight…. Infants born to mothers with pregestational diabetes are more likely to experience adverse outcomes, especially an increased birth weight. Previous studies have shown the importance of strict maternal glycemic control to prevent fetal hyperinsulinemia and accelerated growth. Excessive gestational …

Pilot study shows that an SGLT-2 inhibitor doses of 5-mg and 10-mg were associated with significant reductions in blood glucose and total daily insulin dose…. Dapagliflozin is a member of the SGLT2 inhibitor class of diabetic medications indicated only for treatment of type 2 diabetes. Dapagliflozin helps reduce blood glucose …

For people with type 1 diabetes, long-acting insulin may be a better treatment choice than intermediate-acting insulin…. Different types of insulin are used to manage type 1 diabetes with insulin injections. Long-acting insulin takes about one hour to begin lowering blood sugar levels and lasts up to 26 hours, while intermediate-acting …

Researchers are unsure why the phenotype is increasing but suggest that more effective treatments may be contributing to the increase in non-albuminuric CKD…. Chronic kidney disease (CKD) is a common complication of diabetes associated with glomerular filtration rate (GFR) loss. Normally, before the GFR loss occurs, albuminuria will be detected. …

Promising trial showed safe restoration of near-normoglycemia in type 1 diabetes…. Islet transplantation is a well-established therapeutic treatment for a subset of patients with difficult to control type 1 diabetes mellitus. Before the Edmonton Protocol, only 9% of the 267 islet transplant recipients since 1999 were insulin independent for more …