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Type 1 Diabetes

Type 1 Diabetes Treatment and Research: Type 1 diabetes is an autoimmune disorder that destroys pancreatic beta cells. Once called juvenile diabetes, Type 1 is diagnosed most often in children, but can be expressed in adults as well. Incidence is highest among non-hispanic whites, according to the NDEP. Adults with Type 1 make up 5% of all diagnosed diabetes patients.New tools, techniques, treatments, drugs and devices can help you improve outcomes for your patients with Type 1.

Teaching Muscles to Make Insulin: Could Gene Therapy Rewrite the Future of Type 1 Diabetes?

3D medical illustration showing skeletal muscle engineered through gene therapy to produce insulin, with DNA strands, gene delivery vectors, and glucose regulation concepts representing future treatment for type 1 diabetes.

For more than a century, insulin therapy has remained the cornerstone of treatment for type 1 diabetes. While continuous glucose monitors, insulin pumps, and automated insulin delivery systems have dramatically improved diabetes management, they still do not replace the body’s natural ability to regulate blood sugar. As a result, researchers …

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Could a Mini Pancreas Predict Which Diabetes Drug Will Work Best?

Scientist holding a patient-derived pancreatic organoid in a laboratory with a pancreas model and advanced research equipment, illustrating precision diabetes medicine.

Finding the right diabetes medication often involves trial and error. One patient may respond well to a GLP-1 receptor agonist, while another sees little benefit from the same treatment. As a result, clinicians frequently adjust medications before finding the most effective option. What if doctors could test a patient’s response …

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The Return of C-Peptide: Why This Old Biomarker Is Finding New Clinical Uses

Healthcare professional reviewing C-peptide test results with a pancreatic model, blood sample, and glucose monitoring equipment representing beta-cell function assessment in diabetes care.

For many years, C-peptide testing was viewed as a simple tool to distinguish type 1 diabetes from type 2 diabetes. However, the story has changed. As researchers gain a better understanding of pancreatic beta-cell function, C-peptide testing in diabetes has become much more valuable than a diagnostic aid alone. Today, …

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The Biotin Blind Spot: How Everyday Supplements Can Skew Critical Diabetes Lab Results

High-dose biotin supplement bottle beside diabetes testing supplies, laboratory blood sample, and thyroid and cardiac lab reports illustrating biotin interference with diagnostic testing.

Biotin supplements have become increasingly popular among people living with diabetes. Many individuals take them to support healthy hair and nails, while others use high-dose formulations in hopes of easing neuropathy symptoms. An often-overlooked concern is biotin interference with laboratory tests used in diabetes care. Although biotin itself does not …

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Could “Smart” Insulin End Hypoglycemia? The Race Toward Glucose-Responsive Therapy

Illustration of glucose-responsive insulin technology showing a smart insulin vial, syringe, blood glucose monitor, and molecular structures representing glucose-activated insulin therapy.

For more than a century, insulin has saved millions of lives. Yet despite remarkable advances in diabetes technology, one major challenge remains: preventing hypoglycemia while maintaining excellent glucose control. That is why researchers are developing glucose-responsive insulin, often called “smart” insulin. Instead of delivering a fixed amount of insulin regardless …

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The Future of Type 1 Screening: Will Genetics Replace Autoantibodies?

Pediatric genetic screening for type 1 diabetes showing a DNA helix, blood sample, and clinical risk assessment used for early detection of disease risk.

Population-based screening for type 1 diabetes is entering a new era. While autoantibody testing remains the gold standard for identifying individuals at high risk, researchers are increasingly investigating whether type 1 diabetes genetic screening could identify susceptible people even earlier. Advances in genomic science now make it possible to estimate …

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Could Stem Cell Therapy Change Type 1 Diabetes Forever? Preparing for the Next Era of Care

Illustration of stem cell-derived pancreatic islet cells, a pancreas, and a person with type 1 diabetes using a glucose monitor, representing advances in stem cell islet transplant diabetes therapy.

For more than a century, insulin has been the foundation of type 1 diabetes care. However, even the best insulin pumps, continuous glucose monitors, and automated insulin delivery systems still cannot fully replace the body’s lost beta cells. That is why interest in stem cell islet transplant diabetes research continues …

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The First Disease-Modifying Treatment After a Type 1 Diabetes Diagnosis: Why Teplizumab Is Changing the Conversation

Pediatric endocrinologist discussing teplizumab treatment options with a family following a new type 1 diabetes diagnosis.

For decades, treatment after a type 1 diabetes diagnosis focused almost entirely on insulin replacement and blood glucose management. While advances in technology have improved care, clinicians have had few ways to address the autoimmune process driving beta-cell loss. That is beginning to change. With the FDA’s expansion of teplizumab-mzwv …

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Should Patients Still Be Using Flash CGM? Navigating the Shift to Real-Time Monitoring

Patient with a continuous glucose monitor reviewing glucose data on a smartphone while transitioning from flash CGM to real-time CGM technology.

As diabetes technology continues to evolve, clinicians are increasingly faced with an important question: should patients still be using flash continuous glucose monitoring (CGM), or is it time to switch to real-time CGM? While flash CGM systems have significantly improved glucose monitoring and patient engagement over traditional fingerstick testing, real-time …

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A Positive Type 1 Diabetes Screen Isn’t Always Equal: Why IA-2 Changes the Risk Calculation

Clinical illustration showing IA-2 autoantibody testing, type 1 diabetes risk assessment, blood sample analysis, and patient monitoring strategies used in islet autoantibody screening risk stratification.

As population-based screening for type 1 diabetes (T1D) becomes more common, clinicians increasingly encounter positive islet autoantibody results in children and adults who have no symptoms. However, not all positive screening results carry the same clinical significance. A single positive autoantibody may indicate elevated risk, yet the specific antibody detected …

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