For more than a century, insulin therapy has remained the cornerstone of treatment for type 1 diabetes. While continuous glucose monitors, insulin pumps, and automated insulin delivery systems have dramatically improved diabetes management, they still do not replace the body’s natural ability to regulate blood sugar. As a result, researchers …
Read More »Could a Mini Pancreas Predict Which Diabetes Drug Will Work Best?
Finding the right diabetes medication often involves trial and error. One patient may respond well to a GLP-1 receptor agonist, while another sees little benefit from the same treatment. As a result, clinicians frequently adjust medications before finding the most effective option. What if doctors could test a patient’s response …
Read More »The Return of C-Peptide: Why This Old Biomarker Is Finding New Clinical Uses
For many years, C-peptide testing was viewed as a simple tool to distinguish type 1 diabetes from type 2 diabetes. However, the story has changed. As researchers gain a better understanding of pancreatic beta-cell function, C-peptide testing in diabetes has become much more valuable than a diagnostic aid alone. Today, …
Read More »The Biotin Blind Spot: How Everyday Supplements Can Skew Critical Diabetes Lab Results
Biotin supplements have become increasingly popular among people living with diabetes. Many individuals take them to support healthy hair and nails, while others use high-dose formulations in hopes of easing neuropathy symptoms. An often-overlooked concern is biotin interference with laboratory tests used in diabetes care. Although biotin itself does not …
Read More »Could “Smart” Insulin End Hypoglycemia? The Race Toward Glucose-Responsive Therapy
For more than a century, insulin has saved millions of lives. Yet despite remarkable advances in diabetes technology, one major challenge remains: preventing hypoglycemia while maintaining excellent glucose control. That is why researchers are developing glucose-responsive insulin, often called “smart” insulin. Instead of delivering a fixed amount of insulin regardless …
Read More »The Future of Type 1 Screening: Will Genetics Replace Autoantibodies?
Population-based screening for type 1 diabetes is entering a new era. While autoantibody testing remains the gold standard for identifying individuals at high risk, researchers are increasingly investigating whether type 1 diabetes genetic screening could identify susceptible people even earlier. Advances in genomic science now make it possible to estimate …
Read More »Could Stem Cell Therapy Change Type 1 Diabetes Forever? Preparing for the Next Era of Care
For more than a century, insulin has been the foundation of type 1 diabetes care. However, even the best insulin pumps, continuous glucose monitors, and automated insulin delivery systems still cannot fully replace the body’s lost beta cells. That is why interest in stem cell islet transplant diabetes research continues …
Read More »The First Disease-Modifying Treatment After a Type 1 Diabetes Diagnosis: Why Teplizumab Is Changing the Conversation
For decades, treatment after a type 1 diabetes diagnosis focused almost entirely on insulin replacement and blood glucose management. While advances in technology have improved care, clinicians have had few ways to address the autoimmune process driving beta-cell loss. That is beginning to change. With the FDA’s expansion of teplizumab-mzwv …
Read More »Should Patients Still Be Using Flash CGM? Navigating the Shift to Real-Time Monitoring
As diabetes technology continues to evolve, clinicians are increasingly faced with an important question: should patients still be using flash continuous glucose monitoring (CGM), or is it time to switch to real-time CGM? While flash CGM systems have significantly improved glucose monitoring and patient engagement over traditional fingerstick testing, real-time …
Read More »A Positive Type 1 Diabetes Screen Isn’t Always Equal: Why IA-2 Changes the Risk Calculation
As population-based screening for type 1 diabetes (T1D) becomes more common, clinicians increasingly encounter positive islet autoantibody results in children and adults who have no symptoms. However, not all positive screening results carry the same clinical significance. A single positive autoantibody may indicate elevated risk, yet the specific antibody detected …
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