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Donna Pacheco

GLP-1s and Lean Mass: Preserving Muscle and Strength During Rapid Weight Loss

GLP-1 medications support weight loss, but lean mass loss is a concern. Learn how to protect muscle, strength, and function during GLP-1 therapy.

The scale is moving fast, clothes are fitting better, and blood sugar numbers are improving. For many people using GLP-1 medications, weight loss can feel almost effortless at first. Yet beneath those encouraging changes, another question often emerges: is muscle being lost along with fat? For individuals focused on long-term …

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GLP-1s and Dermatologic Disease: From Psoriasis to Hidradenitis—Signal or Noise?

Dermatologist examining inflammatory skin lesions in a patient using GLP-1 therapy

A patient returns for follow-up after starting a GLP-1 receptor agonist and mentions something unexpected. Their blood glucose is improved, weight is down, and their psoriasis seems quieter. Another patient reports fewer hidradenitis flares. These anecdotes are becoming more common, raising a practical question for clinicians. Are GLP-1 therapies influencing …

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GLP-1s and Inflammatory Arthritis: What Early Signals Mean for Diabetes Care

GLP-1 injection pen next to inflamed knee joints illustrating the relationship between GLP-1 therapy and inflammatory arthritis in diabetes care

A patient with type 2 diabetes finally achieves better glycemic control on a GLP-1 receptor agonist. Weight is coming down, A1C is improving, and cardiovascular risk looks more manageable. Then an unexpected comment appears at a follow-up visit. Their joints feel better. For clinicians, moments like this raise an important …

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GLP-1s and Hypertension: Can Incretins Help Bring Blood Pressure to Goal?

GLP-1 injection pen next to blood pressure monitor showing controlled systolic and diastolic readings

GLP-1–based therapies have quickly become a cornerstone of modern diabetes care. While most clinicians think of these agents for glucose lowering and weight loss, growing evidence suggests they may also support better blood pressure control. For patients living with diabetes and hypertension, that overlap raises an important question. Can GLP-1 …

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Beyond Coverage: How GLP‑1s, Tech, and AI Are Reshaping Diabetes Equity in 2026

Diverse healthcare professionals and patients interacting with diabetes technology, symbolizing equitable access in 2026.

What happens when breakthrough treatments only reach the few who can afford or access them? That’s the growing dilemma in diabetes care. As GLP‑1 medications, digital tools, and AI reshape how we treat this chronic disease, the risk is clear: innovation could deepen inequality if we don’t act intentionally. Equity …

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CKM in the Wild: Applying the 2026 ADA Cardiometabolic Framework to a Real Panel

Three diverse physicians collaborating with digital icons representing heart, kidney, and glucose care, symbolizing CKM ADA 2026 integration.

What happens when a guideline finally reflects the complex realities of patient care? The ADA’s 2026 CKM standards aim to do just that—merging heart, kidney, and metabolic health into one actionable framework. But translating those recommendations into daily clinical decision-making isn’t always straightforward. This article walks through real-world composite cases …

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AI‑First Clinics: What Happens When Algorithms Drive Most of the Diabetes Visit?

A doctor and patient discussing diabetes care with a futuristic AI dashboard displaying CGM and treatment data in a modern clinic.

What if your next diabetes appointment started before you even walked in—an algorithm already having reviewed your CGM data, flagged risks, and drafted a care plan? That’s not science fiction. It’s the emerging reality of AI-powered workflows for diabetes care, where intelligent systems work behind the scenes to support clinicians …

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Talking About Off‑Label GLP‑1 Use: How to Answer Patients Without Overpromising

Doctor discussing GLP-1 off-label medication options with a patient in a clinical setting, with injection pens and research charts visible.

A patient walks into your exam room, hopeful after reading that a diabetes drug might help with memory loss, addiction, or even anxiety. You know they’re talking about GLP‑1s—but how do you respond when the science is still unfolding? As GLP‑1 receptor agonists capture public attention for much more than …

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