GLP-1 receptor agonists have transformed type 2 diabetes care, improving glycemic control, supporting weight loss, and reducing cardiovascular risk. However, disparities in GLP-1 use and access are becoming harder to ignore. Why do some patients gain access quickly while others face barriers at every step? Data suggest that prescribing patterns …
Read More »Donna Pacheco
GLP-1s and Reproductive Health: What to Know About Fertility, Pregnancy, and PCOS
GLP-1 receptor agonists are transforming diabetes and obesity care. However, as more women of reproductive age use medications like semaglutide, liraglutide, and tirzepatide, questions about how GLP-1 therapies affect fertility and pregnancy are becoming increasingly common. Can patients conceive safely while taking these agents? Do they improve ovulation in women …
Read More »Managing GLP-1 GI Side Effects Before Stopping Therapy
GLP-1 receptor agonists have transformed type 2 diabetes care. Yet for many patients, gastrointestinal side effects from GLP-1 therapy, such as nausea, vomiting, and constipation, can threaten long-term adherence. Have you ever had a patient achieve an impressive A1C reduction but consider stopping therapy because of persistent nausea? You are …
Read More »Off-Ramp Planning for GLP-1s: When and How to Taper Without Losing Progress
As more patients succeed on GLP-1 therapy, conversations about tapering these medications are becoming increasingly common in metabolic care. When patients reach meaningful goals in weight reduction, A1C improvement, or cardiometabolic risk, clinicians naturally begin asking what comes next. Is it safe to stop treatment? More importantly, can progress be …
Read More »GLP-1s and Food Noise: Helping Patients Understand Hunger, Cravings, and Control
Patients taking GLP-1 receptor agonists often describe a surprising change: the “volume” of food thoughts seems to turn down. This experience, often described as a reduction in food noise with GLP-1 therapy, reflects measurable neuroendocrine shifts in appetite regulation and reward signaling. For clinicians, understanding and explaining this phenomenon is …
Read More »GLP-1s in Young Adults: Rethinking Metabolic Risk and Early Intervention
For years, GLP-1 receptor agonists have been associated with older adults who already have type 2 diabetes or established cardiovascular disease. However, metabolic dysfunction does not suddenly appear at age 60. In fact, obesity, insulin resistance, and prediabetes often begin decades earlier. That is why conversations around GLP-1 therapy in …
Read More »Social Determinants First: Using CKM and SDOH to Sequence Diabetes Therapies in 2026
A patient’s A1C can look acceptable on paper while everything else is quietly heading in the wrong direction. Cardiovascular risk is rising, kidney function is slipping, and the patient keeps missing follow-up visits because of cost, transportation, or work constraints. Most clinicians have seen this scenario play out, even when …
Read More »AI for Diabetes in the Community: Bringing Decision Support Beyond the Specialty Clinic
A missed diagnosis, a delayed follow-up, or a rushed primary care visit can quietly shape the course of diabetes for years. For many patients, especially those outside specialty clinics, these small gaps add up. The challenge is not a lack of clinical knowledge, but a lack of timely support where …
Read More »Diabetes Care in the GLP-1 Era: Re-Designing Visits When One Drug Does So Much
GLP-1 receptor agonists have changed diabetes care faster than almost any therapy in recent history. In many ways, one medication now touches glucose control, weight loss, cardiovascular risk, and even liver health. However, while outcomes have evolved, the typical clinic visit has stayed the same. As a result, clinicians often …
Read More »GLP-1s and Serious Mental Illness: Tackling Antipsychotic-Associated Weight Gain
For many patients, antipsychotic medications are life-changing, even life-saving. Yet the same treatments that stabilize mood and thought can quietly drive weight gain, insulin resistance, and rising cardiometabolic risk. Over time, this unintended consequence places patients with serious mental illness at a much higher risk for obesity, type 2 diabetes, …
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