Patients with depression or diabetes have an increased risk of MI, but the risk is even higher in patients with both conditions, according to a new study.…
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Menu Labels Don’t Influence Students’ Food Choices
Menu labels on college cafeteria food — highlighting the good and the bad of various meal options — make no difference in students’ choices, a new study concludes.…
Read More »NIH Findings Have Potential to Curb Obesity and Type 2 Diabetes
Discovery makes white fat mimic energy-burning brown fat, muscle.…
Read More »Letter from the Editor #581: Exenatide News and Type 1 News from the ADA
There was a news release that caught my attention this past week. Eli Lilly announced that the Exenatide tQT Study Showed No Prolongation of QT Interval (See this week’s Item #1). Back in March most of us thought that the FDA would approve the once weekly dose, but instead they …
Read More »GLP-1 Knowledge Survey Part III
This week we examine more of your responses regarding GLP-1 therapy…. See more GLP-1 Agonist Resources. I was glad to see that almost everyone realized that when a GLP-1 agonist is added to a sulfonylurea that it is not the GLP-1 agonist that is responsible for any side effects. It’s …
Read More »GLP-1 Special Series #5 Editor’s Note
This week in Part 3 of our Case Study, Mr. Walker and his wife return for a follow-up visit as his glucose control has not improved as much as expected. Click here to see if you agree with the drug choice. In our analysis of the GLP-1 survey data, we …
Read More »ADA: Safety and Efficacy of Once-Monthly Exenatide over 20 Weeks in Patients with Type 2 Diabetes
Exenatide, a GLP-1 receptor agonist, improves glycemic control and body weight with twice daily or once weekly subcutaneous (SC) injections in patients with type 2 diabetes (T2DM)….
Read More »ADA: Linagliptin Has Similar Efficacy to Glimepiride but Improved Cardiovascular Safety over 2 Years in Patients with Type 2 Diabetes Inadequately Controlled on Metformin
Type 2 diabetes mellitus (T2DM) often requires combination therapy to maintain glycemic control. Adding a sulfonylurea to metformin therapy improves glycemic control, but can cause hypoglycemia and weight gain. This 2-yr double-blind trial investigated the long-term efficacy and safety of adding linagliptin or glimepiride to ongoing metformin to treat T2DM….
Read More »ADA: Exenatide/Diet vs. Diet Alone for Treatment of Prediabetes
Exenatide yields beta cell improvement and weight loss in individuals with diabetes but has not been well-studied in individuals with prediabetes….
Read More »ADA: Efficacy and Safety of Lixisenatide Once-Daily vs. Exenatide Twice-Daily in Type 2 DM Inadequately Controlled on Metformin (GetGoal-X)
This randomized, open-label, parallel-group, multicenter, 24-wk main treatment study, followed by a variable extension of at least 52 wk, compared the efficacy and safety of lixisenatide 20 µg QD and exenatide 10 µg BID in 634 T2DM patients insufficiently controlled on metformin ≥1.5 g/day (mean age 57.4 yr, diabetes duration …
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