A fall in insulin dose requirement in patients with preexisting diabetes can lead to increased risk of placental dysfunction… Women with preexisting diabetes typically experience an increased need for insulin during the later stages of pregnancy due to an increase in insulin resistance during this time. A drop in insulin …
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The Impact of Mediterranean Diets on Metabolic Syndrome
A supplemented Mediterranean diet can lead to metabolic syndrome reversal…. Metabolic syndrome is characterized by risk factors that increase an individual’s chances for cardiovascular disease. These risk factors include obesity, hypertension, high cholesterol and uncontrolled blood glucose. In addition to cardiovascular disease, those with metabolic syndrome are at increased risk …
Read More »Grapefruit Juice May Affect Insulin Resistance
Drinking grapefruit juice daily can lead to weight loss and help control blood glucose… Grapefruit juice is considered to be high in nutrients while remaining relatively low in calories when compared to other fruit juices. These diets often rely on daily low calorie commitment, which calls into question the true …
Read More »Light Technology May Be Used to Control Type 2 Diabetes
Use of blue LED light activates sulfonylureas… The use of sulfonylureas has long been an option for controlling type 2 diabetes. Their use is often associated with hypoglycemia and weight gain. A new technology seeks to minimize these side effects. Researchers are looking at a prototype sulfonylurea, JB253, which stimulates …
Read More »Blocking a Genetic Variant Associated with Type 2 Diabetes May Improve Insulin Secretion
Yohimbine, a α2A-adrenergic receptor agonist, showed a 29% increase in insulin secretion in patients with type 2 diabetes related to the genetic variation… The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type …
Read More »Iron-rich Foods May Put Night Workers at Greater Risk of Diabetes
The researchers found that dietary iron plays an important role in the circadian clock of the liver. “Iron is like the dial that sets the timing of the body clock,” said lead author Judith Simcox from the University of Utah in the US. The liver’s circadian clock is set by …
Read More »Diabetes Patients Have a Poor Response to Stress
Type 2 diabetes patients exhibited a weak ability to regulate blood pressure, cholesterol and heart rate when they experienced stress, a new study showed. Researchers also noted increased depressive and hostile symptoms in these patients. The researchers looked at the biological systems of 140 patients with type 2 diabetes and …
Read More »High-intensity Statin Treatment Improves Diabetic Coronary Atherosclerosis
Cleveland Clinic researchers found that high-intensity statin treatment was associated with coronary atheroma regression in patients with or without diabetes, suggesting the therapy may halt the progression of diabetic coronary atherosclerosis. Coronary atheroma volume was measured using serial intravascular ultrasound in patients treated with rosuvastatin 40 mg or atorvastatin 80 …
Read More »Trulicity Once-Weekly GLP-1 Shipping Now
Trulicity Once-Weekly GLP-1 Shipping Now Eli Lilly and Company announced that Trulicity, a glucagon-like peptide-1 receptor agonist (GLP-1 RA) with once-weekly dosing in the Trulicity pen, was approved by the FDA on September 18, 2014, and is shipping to distributors now.
Read More »Editor’s Note, SGLT-2 Inhibitors Special Edition, October 2014
Sometimes it seems as if we don’t talk about an organ or a problem until we have a medication to treat it. For years we didn’t consider the kidney as a problem area for diabetes. It was not until we identified the SGLT-1 and -2 receptors that we began to …
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