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Diabetes In Control

Reduction of Renal Function and Exercise Capacity in Type 1 Diabetic Adolescents

Insulin resistance with increasing LDL cholesterol were related to low peak volume of oxygen level… Diabetic nephropathy and cardiovascular disease are strongly related in adults with type 1 diabetes, yet little is known about this relationship in adolescents prior to the onset of detectable clinical disease. The researchers hypothesized that …

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High Calorie Consumption after GDM Leads to Increased Insulin Resistance in Hispanic Women

The women also experienced reduced beta cell function…. Researchers from the University of Southern California, Los Angeles, assessed associations between dietary intake and rates of change in insulin resistance and β-cell function in Hispanic women with prior gestational diabetes mellitus (GDM). Sixty-two nondiabetic Hispanic women with pregnancies complicated by GDM …

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Phentermine and Topirimate ER (Qsymia) Studied for Type 2 Diabetes Patients

Diabetic patients can lose weight with medication specific for weight loss... In two randomized, double-blind and placebo-controlled studies, the safety and efficacy of treatment with phentermine (PHEN) and topiramate ER (TPM ER) (Qsymia) plus lifestyle for weight loss and glycemic benefits were measured. The studies included obese/overweight adults with type 2 diabetes. …

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Beloranib Demonstrates Weight Loss in Hypothalamic Injury-Associated Obesity

The drug, a first-in-class MetAP2 inhibitor, was well-tolerated and also improved cardiovascular disease risk factors… Zafgen has announced that ZAF-221, a randomized, double-blind, placebo-controlled Phase 2 clinical trial of beloranib, a MetAP2 inhibitor, in 14 adults with hypothalamic injury associated obesity, or HIAO, met the primary efficacy endpoint of weight …

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Type 2 Diabetes Increased Risk for Colorectal Cancer

Dutch researchers evaluated data on 300,039 type 2 adults on at least one prescription for an antidiabetes drug, and a comparison cohort without diabetes (controls) to determine the relationship between type 2 diabetes and colorectal cancer. “We observed a moderate, yet (1.3-fold) significantly increased, risk of colorectal cancer in patients …

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Women with PTSD Have Higher Risk for Type 2 Diabetes

In this 22-year study of women, symptoms of post-traumatic stress disorder (PTSD) were associated with the incidence of type 2 diabetes in a dose-dependent manner. The authors conclude that women with PTSD were at a twofold increased risk for having type 2 diabetes than counterparts without PTSD, and thus care …

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