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Diabetes In Control

54 Drugs with Weight Changes

Researchers examined data from 257 randomized trials to find out which drugs cause weight loss… Researchers conducted a systematic review and meta-analysis to summarize the evidence about commonly prescribed drugs and their association with weight change. MEDLINE, DARE, and the Cochrane Database of Systematic Reviews were searched to identify published …

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Does Detemir Cross the Placenta in Women with Diabetes?

The relatively new long-acting insulin analog needs to be studied to determine its absorption pharmacokinetics… Insulin detemir (IDet) is a relatively new long-acting insulin analog that offers improved absorption pharmacokinetics and slower tissue distribution due to high plasma protein binding. As IDet is increasingly used for treatment of insulin-requiring diabetes, …

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Intensive Lifestyle Weight-loss Intervention and Metformin in the Diabetes Prevention Program

In the DPP and DPP-OS trials, diabetes was prevented or delayed with metformin or ILS when directed at weight loss and increased physical activity… Previous randomized clinical trials such as the Diabetes Prevention Program and the long-term follow-up trial, the Diabetes Prevention Program Outcomes study, evaluated metformin and an intensive …

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Effects of GIP and GLP-1 on Glucagon Response in Type 1 Diabetes

Glucose-dependent insulinotropic polypeptide and glucagon- like peptide-1 have glucose-dependent effects on glucagon secretion but differ in their effects on type 1 and type 2 diabetes patients… From various studies we know that glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have glucose-dependent effects on glucagon secretion. GIP causes increased glucagon …

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Deaf People at Higher Risk of Type 2 Diabetes

Inadequate access to primary care means that deaf people have a higher risk of developing type 2 diabetes, high blood pressure, and heart disease… The research, conducted at the School for Social and Community Medicine at the University of Bristol, compared the health of deaf people to that of people …

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High-Protein Diets Yield Mixed Results

Popular weight loss strategy improves satiety and decreases fat mass, but increases risk of metabolic disease… Some of the potential mechanisms that account for weight loss associated with high-protein diets involve increased secretion of satiety hormones (GIP, GLP-1), reduced orexigenic hormone secretion (ghrelin), the increased thermic effect of food and …

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