Why is cancer risk higher among diabetes patients?… Evidence indicates an increased risk of certain cancers among people with type 2 diabetes. Evidence for rarer cancers and for type 1 diabetes is limited. Australian researchers recently explored the excess risk of site-specific cancer incidence and mortality among people with type …
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54 Drugs with Weight Changes
Researchers examined data from 257 randomized trials to find out which drugs cause weight loss… Researchers conducted a systematic review and meta-analysis to summarize the evidence about commonly prescribed drugs and their association with weight change. MEDLINE, DARE, and the Cochrane Database of Systematic Reviews were searched to identify published …
Read More »Does Detemir Cross the Placenta in Women with Diabetes?
The relatively new long-acting insulin analog needs to be studied to determine its absorption pharmacokinetics… Insulin detemir (IDet) is a relatively new long-acting insulin analog that offers improved absorption pharmacokinetics and slower tissue distribution due to high plasma protein binding. As IDet is increasingly used for treatment of insulin-requiring diabetes, …
Read More »Keeping Blood Sugars Down May Delay Type 1 Diabetes Complications
Optimum HbA1c level yet to be determined… HbA1c is strongly related to the development of diabetes complications, but it is still controversial as to which HbA1c level to strive for in the treatment of type 1 diabetes. Swedish researchers evaluated HbA1c, followed from diagnosis, as a predictor of severe microvascular …
Read More »Intensive Lifestyle Weight-loss Intervention and Metformin in the Diabetes Prevention Program
In the DPP and DPP-OS trials, diabetes was prevented or delayed with metformin or ILS when directed at weight loss and increased physical activity… Previous randomized clinical trials such as the Diabetes Prevention Program and the long-term follow-up trial, the Diabetes Prevention Program Outcomes study, evaluated metformin and an intensive …
Read More »Higher Prevalence of Suicide Attempts in Adolescent Type 1 Diabetes Patients
However, advancement in medications and better controlled regimens may be contributing to a decline in psychiatric disorders among this population… We know from previous studies and research that there is a increased risk and prevalence for depression in the diabetic population. Other trials have also linked diabetes with different subtypes …
Read More »Effects of GIP and GLP-1 on Glucagon Response in Type 1 Diabetes
Glucose-dependent insulinotropic polypeptide and glucagon- like peptide-1 have glucose-dependent effects on glucagon secretion but differ in their effects on type 1 and type 2 diabetes patients… From various studies we know that glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have glucose-dependent effects on glucagon secretion. GIP causes increased glucagon …
Read More »Do Anxiety, Depression and Metabolic Syndrome Increase the Risk of Type 2?
Depressive symptoms have been associated with type 2 diabetes mellitus (T2DM), but less is known about other anxiety disorders that can be comorbid or exist without depression… This study examined patients at risk for type 2 diabetes and its correlation to anxiety, depression or metabolic syndrome in the at risk …
Read More »Deaf People at Higher Risk of Type 2 Diabetes
Inadequate access to primary care means that deaf people have a higher risk of developing type 2 diabetes, high blood pressure, and heart disease… The research, conducted at the School for Social and Community Medicine at the University of Bristol, compared the health of deaf people to that of people …
Read More »High-Protein Diets Yield Mixed Results
Popular weight loss strategy improves satiety and decreases fat mass, but increases risk of metabolic disease… Some of the potential mechanisms that account for weight loss associated with high-protein diets involve increased secretion of satiety hormones (GIP, GLP-1), reduced orexigenic hormone secretion (ghrelin), the increased thermic effect of food and …
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