Patient, type 2 diabetes and obesity, on basal/bolus insulin with an A1C of 10.7%. He was not following any particular meal plan, and was, for the most part, consuming a high carb diet. Diabetes education was provided, including how carbohydrates affect glucose levels, lowering his carbs, and ideal target glucose levels. We told him we did not expect him to reach these levels right away, in fact we wanted to see how he adjusted to the change in diet without low glucose levels, so we recommended he decrease both his basal and bolus insulin, with clear instructions on how much insulin to take...

In this week's Homerun Slides, we see how sulfonylureas, metformin and TZDs work in the treatment type 2 diabetes...

Single-tablet approach hoped to boost treatment compliance and help patients better manage condition.. Synjardy contains empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin, a biguanide. It is not for the treatment of type 1 diabetes or diabetic ketoacidosis. The drug label contains a boxed warning on the risk of …

Risk warning, precaution added to labels of all drugs in this class…   FDA warned recently that DPP-4 inhibitors could cause severe and disabling joint pain. The agency has added a new warning and precaution about this risk to the labels of all drugs in this class. If patients experience …

Study cites vascular, nonvascular causes…. The purpose of this study was to assess the odds of all-cause mortality in individuals with diabetic foot ulceration (DFU) compared with those with diabetes and no history of DFU. In addition, we sought to determine the strength of association of DFU with cardiovascular and …

Researchers seek link between glycemic control and new CV events and mortality… The findings, based on 1,687 adults, also revealed about a 16% increased risk for all-cause mortality with every 1% increase in A1C levels among diabetes patients with and without vascular disease. There was no difference in relationship among …

Adding liver fibrosis to the long list of diabetic complications under consideration… A recent study published in Hepatology evaluated various risk factors for liver fibrosis in a Dutch population. The call for concern is the prevalence of liver fibrosis in a patient population with low prevalence of hepatitis—the usual suspect …

New study suggests respiratory research in diabetes patients needs to be done differently in future… Diabetes has been known to cause respiratory problems in patients. Often aerobic and endurance training is encouraged to counteract this issue. Current respiratory research in diabetes patients has focused on diaphragm muscles and other skeletal …

Research pinpoints molecular link between insulin resistance and mitochondrial changes… A recent study published in Clinical Epigenetics said researchers sought to discover if they could find any biomarkers in a group of patients with no pre-existent diabetes or cardiovascular disease, but indication of prediabetes and insulin resistance. Researchers analyzed data …

Reduced risk of heart attacks, strokes, cardiovascular events suggested.