TOP STORIES — Diabetes News and Research
Physical Activity and Inflammatory Markers in Prediabetes
Letter from the Editor
We have always known that patients with diabetes are more likely to get infections, and they are usually more severe. The pandemic that we are just starting to emerge from has certainly proven that, as patients with diabetes were more likely to contract the coronavirus, more likely to be hospitalized, and more likely to die. This can be explained by the increased risk these patients have for respiratory diseases like pneumonia.
With these factors in mind, is the diagnosis the problem, or the severity of the diabetes measured by A1c levels? This week, Shalonda Kimble, PharmD Candidate, South College School of Pharmacy, has looked at the information and found out there is a relationship, and knowing what numbers to treat your patients to may make a big difference.
Check out her feature to find that number.
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We can make a difference!
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Dave Joffe
Editor-in-chief
TOP STORIES — Diabetes News and Research
A systematic review and meta-analysis of randomized controlled trials examines how some inflammatory markers may be affected by physical activity.
Twenty insulin sensitivity indices compared to determine the superior predictor of type 2 diabetes development in Japanese Americans.
Study finds that each 1% elevation in HbA1c increased risk for cellulitis in diabetes patients.
Did You Know: Which Fruit Cuts Cardiometabolic Risk in Obesity?
Commonly consumed whole berry fruits, especially blueberries and strawberries, have been noted for their distinct effects in improving metabolic syndrome. Most of the health benefits have been explained by their high polyphenol and fiber content and concomitant low caloric contributions to the diet. Metabolic syndrome, with elevated blood lipids such as total and LDL cholesterol, remains a prominent global health issue. Dietary berries have been demonstrated to reduce these risks in clinical trials.
A study in the journal Nutrients found that adults with obesity and high low-density lipoprotein cholesterol levels who consumed freeze-dried strawberry supplements (equivalent to 2.5 servings of strawberries) every day for four weeks experienced reductions in serum insulin, and concomitant insulin resistance, compared with controls. The findings also suggest that dose increased serum glucagon and decreased serum plasminogen activator inhibitor-1 levels.
The 2.5 serving dose of strawberries also resulted in improvements in lipid particle concentrations, especially in decreasing VLDL and chylomicron particles, as well as total and small LDL particles, all of which have significant consequences in reducing atherogenic risk in these adults. The trial also supports the hypothesis that dietary strawberries, when consumed at a dose of two-and-a-half servings a day, significantly improve cardiometabolic risks, mainly via improving insulin resistance and atherogenic lipid particles, when compared to the control group. Even at a dose of one serving of strawberries, modest effects were observed for improving HDL particle size. These findings support the role of dietary strawberries in a medical nutrition therapeutic approach for diabetes prevention in adults.
Source: Nutrients. ”Dietary Strawberries Improve Cardiometabolic Risks in Adults with Obesity and Elevated Serum LDL Cholesterol in a Randomized Controlled Crossover Trial.”
Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:
Oluwatayo Ishola, PharmD. Candidate, South College, School of Pharmacy
Shalonda Kimble, PharmD Candidate, South College School of Pharmacy
Laura Martínez López, PharmD. Candidate 2021, Lake Erie College of Osteopathic Medicine, College of Pharmacy
Brenda Oppong, PharmD Candidate, LECOM School of Pharmacy
Destiny Reed, PharmD. Candidate, Florida A&M College of Pharmacy and Pharmaceutical Sciences
Peter Jay Won, Pharm.D. Candidate, University of South Florida, Taneja College of Pharmacy
Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
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