Intensive Lifestyle Intervention Leads to Moderate Bone Loss in Men with Diabetes vs. Women

Men showed slightly greater hip-bone loss at four years than did those in the diabetes support and education cohort. However, researchers did not observe a similar trend in women with diabetes. The trial randomized 1,309 overweight and obese individuals with type 2 diabetes to an intensive lifestyle intervention (ILI) versus a diabetes support and education (DSE) intervention. "A four-year weight loss intervention was significantly associated with a modest increase in bone loss at the hip in men but not in women," the authors write. Diabetes Care 2014