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Monthly Archives: August 2016

Lantus Biosimilar

When the Biosimilar insulin to Lantus becomes available for about 10-15% less cost, will you recommend it to your patients? Follow the link to share your opinion!

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Question #847

Test Your Knowledge

Weight loss has been shown to have a positive impact on glucose control and cardiovascular risk factors. At which weight loss threshold do these positive benefits start to become meaningfully apparent? A) Weight reduction of 0-4% B) Weight reduction of 5-10% C) Weight reduction of 11-15% D) Weight reduction of 16-20% Did you get it right? Follow the link to find out!

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August 18, 2016

For years the crux of diabetes care for type 2’s has been to reduce the amount of glucose going in and the amount of glucose being absorbed. We put patients on carbohydrate-restricted diets, have them take fiber before a meal, and use medicines such as acarbose. For the most part …

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August 16, 2016

If you are still stuck on the “metformin to start with and max out the dose” diabetes treatment algorithm, then you’d better take a look at this week’s homerun slides. Considering there are 11 distinct pathways to developing diabetes, it doesn’t make any sense that all our patients would only have …

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Always Ask What Type

Female, 32 years of age, well aware of the fact she had type 1 diabetes, was suicidal, who reported she chose to stop taking her insulin a few days earlier. Was taken to the police station on a warrant (unknown reason), who took her to the ED due to her report of suicidal ideation. She was found to be hyperglycemic at that time, but did not say she had type 1. Acetone was negative. Given 5 units regular insulin and sent back with police. She then started complaining of not feeling well, taken back to ED, no treatment and sent back with police. The next morning, complained of nausea, vomiting, and abdominal pain.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #37: Normal Beta-cell Function Part 2 of 6

Beta-Cell response to intravenous glucose: Although in normal living conditions beta cells are stimulated by hyperglycemia that follows glucose ingestion, the study of the response to intravenous glucose is of fundamental importance for understanding the physiology of beta cells. Several tests have been developed for this purpose and this section describes the most relevant and the characteristics of insulin secretion that they reveal.

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August 13, 2016

Last week the FDA announced that they were going to approve 6 different manufacturers for the production of rosuvastatin calcium, the generic version of Crestor. It appears that the FDA has decided that if they let more companies produce the generic, the price may not be as high to start …

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