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Type 1 Diabetes and New Innovations

Jun 26, 2021
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Brenda Oppong, PharmD Candidate, LECOM School of Pharmacy

A century after the discovery of insulin, new insulins, new devices, and other innovations may again change the future of treatment for type 1 diabetes. 

Insulin was discovered in 1921 for the treatment of patients with type 1 diabetes (T1D) and has continued to develop and transform. Before the introduction of recombinant human insulin that prompted the development of newer insulins, animal insulins were used to treat T1D for over 60 years. The innovations for the treatment of T1D are endless, ranging from oral and weekly insulins and smart insulins to the development of insulin analogs, glucose sensors, closed-loop insulin delivery devices, and more. The continual progression and development in the treatment, prevention, and prediction of T1D emphasize the ongoing challenges of eliminating or potentially altering the nature and history of T1D. A recent issue of Diabetologia describes the significant advances in the science of T1D while highlighting challenges and barriers.  


Investigational once-weekly insulin was assessed in a 26-week phase II trial....

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