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Treating Prediabetes Prevents Functional Decline

May 15, 2021
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Brenda Oppong, PharmD Candidate, LECOM School of Pharmacy

Older adults with prediabetes or diabetes experienced faster physical functional decline and disability progression. 

Diabetes is associated with a higher risk of faster physical functional decline, but the impact of prediabetes has been unknown. Individuals with physical function decline are regarded to be in a pre-disability phase. A population-based cohort study compared the effects of diabetes and prediabetes on physical function and disability progression, and whether cardiovascular diseases (CVDs) have an association. Although there have only been a few previous studies on the association of prediabetes with poor physical function, the results have been inconsistent. A study in the U.K. observed that impaired glucose tolerance was associated with a 60% higher possibility of poor physical function. On the other hand, a Japanese study concluded there was no association between prediabetes, walking speed, and chair stand time. These discrepancies may be due to different measurements of physical function and prediabetes....


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