Your patient has been newly diagnosed with type 2 diabetes (A1C 7.7%) and you have prescribed metformin. Metformin should be titrated to minimize which side effect?
Answer: D. Gastrointestinal-side effects
If well tolerated and not contraindicated, metformin is considered the preferred first-line treatment for TYPE 2 DIABETES. While generally well tolerated, gastrointestinal side effects are considered a common problem unless metformin is titrated.
Inzucchi S, et al. Management of hyperglycemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2012; 35(6):1364-1379.