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Tag Archives: pediatric endocrinology

The First Disease-Modifying Treatment After a Type 1 Diabetes Diagnosis: Why Teplizumab Is Changing the Conversation

Pediatric endocrinologist discussing teplizumab treatment options with a family following a new type 1 diabetes diagnosis.

For decades, treatment after a type 1 diabetes diagnosis focused almost entirely on insulin replacement and blood glucose management. While advances in technology have improved care, clinicians have had few ways to address the autoimmune process driving beta-cell loss. That is beginning to change. With the FDA’s expansion of teplizumab-mzwv …

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A Positive Type 1 Diabetes Screen Isn’t Always Equal: Why IA-2 Changes the Risk Calculation

Clinical illustration showing IA-2 autoantibody testing, type 1 diabetes risk assessment, blood sample analysis, and patient monitoring strategies used in islet autoantibody screening risk stratification.

As population-based screening for type 1 diabetes (T1D) becomes more common, clinicians increasingly encounter positive islet autoantibody results in children and adults who have no symptoms. However, not all positive screening results carry the same clinical significance. A single positive autoantibody may indicate elevated risk, yet the specific antibody detected …

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Type 1 Diabetes Prevention in Younger Patients: What New Data Mean for Screening

Pediatric doctor discussing early screening and type 1 diabetes prevention with a mother and child in a clinical setting

Can we actually prevent type 1 diabetes before symptoms appear? Increasingly, the answer is yes. As research evolves, clinicians now have stronger tools to identify at-risk children earlier and delay disease progression. This shift is especially important because type 1 diabetes often develops silently before diagnosis. Therefore, early screening and …

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