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Tag Archives: gastrointestinal side effects

GLP-1s and Opioids: The GI Risk Clinicians May Be Missing

GLP-1 medications and opioid therapy representing potential gastrointestinal risks from concurrent treatment.

GLP-1 receptor agonists have transformed the treatment of type 2 diabetes, but their effects on gastrointestinal motility remain an important clinical consideration. Opioids can also slow gastrointestinal function, raising an obvious question: what happens when patients need both? New research examining GLP-1 and opioid interactions suggests that opioid choice may …

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GLP-1 Risk Stratification: Which Patients Are More Likely to Develop Side Effects?

Doctor explaining GLP-1 side effect risk factors to a patient using a visual chart with medication tools on a desk

The risk of side effects with GLP-1 therapies varies widely among patients, yet treatment decisions often overlook this variability. Why do some patients tolerate GLP-1 receptor agonists with ease while others discontinue early? Much like how individuals respond differently to diet or exercise, medication tolerance is influenced by a mix …

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Managing GLP-1 GI Side Effects Before Stopping Therapy

Physician discussing GLP-1 GI side effects and nausea management with a patient during a diabetes consultation

GLP-1 receptor agonists have transformed type 2 diabetes care. Yet for many patients, gastrointestinal side effects from GLP-1 therapy, such as nausea, vomiting, and constipation, can threaten long-term adherence. Have you ever had a patient achieve an impressive A1C reduction but consider stopping therapy because of persistent nausea? You are …

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