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Tag Archives: endothelial dysfunction

A Newly Discovered Form of Cell Death May Explain Why Diabetes Causes So Many Complications

Scientific illustration showing ferroptosis, an iron-dependent form of cell death, contributing to diabetic complications affecting the kidneys, eyes, nerves, and heart.

Diabetes is known for raising blood sugar levels, but its long-term complications often have the greatest impact on health. Kidney disease, vision loss, nerve damage, and cardiovascular disease affect millions of people living with diabetes. For years, researchers focused on inflammation, oxidative stress, and poor circulation to explain these complications. …

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The Blood Vessel Damage Doctors Can’t See—Until It’s Too Late

Medical illustration showing the endothelial glycocalyx lining healthy blood vessels with a magnified view of microscopic vascular damage associated with diabetes.

Most people think diabetes-related blood vessel damage begins only after years of high blood sugar. However, scientists are uncovering evidence that injury may start much earlier, in a structure so thin it cannot be seen during a routine medical exam. This microscopic layer, known as the endothelial glycocalyx, acts as …

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