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Tag Archives: A1C

GLP‑1s and Liver Disease: Rethinking MASLD Care Beyond Obesity and A1C

3D liver with fatty deposits, GLP-1 injection pen, stethoscope, molecular structures, and test results for liver enzymes

Nonalcoholic steatohepatitis (NASH) and metabolic dysfunction–associated steatotic liver disease (MASLD) are rapidly becoming leading causes of chronic liver disease worldwide. Traditionally, clinicians have associated MASLD with obesity, insulin resistance, and type 2 diabetes, often using body mass index (BMI) and A1C as screening triggers. However, an important shift is occurring …

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From A1C to TIR – Rethinking Glycemic Targets for Better Long‑Term Outcomes

A glucose meter reading 117 mg/dL placed over lab results showing Hemoglobin A1c and a Time in Range (TIR) chart with green, yellow, and red bars.

For decades, clinicians have relied on A1C as the primary benchmark for diabetes control. Yet many patients and providers now wonder: does a single quarterly number truly reflect daily glucose fluctuations and risks? As continuous glucose monitoring (CGM) becomes more accessible, the metric known as Time in Range (TIR) has …

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