Neuropathy & Pain

Researchers suggested that, switching to duloxetine (Cymbalta) or pregabalin (Lyrica) can produce pain relief for patients with diabetic neuropathy who stop responding to gabapentin (Neurontin)….

The finding may eventually lead to new ways to fight neuropathy, a condition that often accompanies other diseases including HIV/AIDS, diabetes and circulatory disorders….

Chronic metformin use results in vitamin B12 deficiency in 30% of patients. Exhaustion of vitamin B12 stores usually occurs after twelve to fifteen years of absolute vitamin B12 deficiency…. Vitamin B12 deficiency, which may present without anemia and as a peripheral neuropathy, is often misdiagnosed as diabetic neuropathy, although the …

Several effective treatments are available for painful diabetic neuropathy. The current study provides important insight into treatment choice by comparing two effective medications in patients with painful diabetic neuropathy. The results of this trial should help physicians tailor the best therapy for individual patients.

The purpose of the study is to summarize evidence about the diagnostic accuracy of the 5.07/10-g monofilament test in peripheral neuropathy.

Diabetic Peripheral Neuropathy (DPN: peripheral nerve damage) is a common complication of diabetes. Almost 70% of people with diabetes develop DPN within five years and after five, years the incidence rate increases to almost 100%. DPN most often begins as a tingling feeling and insidiously progresses to loss of sensation …

The antiepileptic drug lacosamide is effective in reducing painful diabetic neuropathy without serious side effects, according to results from two phase 3 trials, one in the United States and one in the European Union, researchers reported at the American Academy of Neurology (AAN) 61st Annual Meeting.

Intranasal insulin slows the progression of diabetic peripheral neuropathy. Peak blood concentrations of insulin were nearly 1000-fold lower after intranasal delivery than after subcutaneous delivery.

Duloxetine, pregabalin, and gabapentin offer similar efficacy for patients with diabetic peripheral neuropathic pain, according to a new report. 

New research indicates that even in the absence of peripheral neuropathy, patients with long-standing diabetes mellitus are prone to impaired ankle function.