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Cardiology

Cardiovascular Health and Diabetes: Diabetes is an inflammatory, cardiometabolic disease. It elevates nearly every cardiovascular risk factor, and most diabetes patients will die from cardiovascular disease. However, insights from new clinical research along with patient education provide new edges to improve cardiovascular outcomes in your diabetes patients.

Insulin Omission for Weight Loss in a Female Adolescent Treated With Advanced Hybrid Closed-Loop System

In a recent article published in the journal Diabetes Care, researchers from Israel reported on a case of a female adolescent with type 1 diabetes who was intentionally omitting insulin in an attempt to lose weight. The adolescent was treated with an advanced hybrid closed-loop system (AHCL), which is a …

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Blood Pressure Target in Type 2 Diabetes Mellitus

Abstract  The prevalence of diabetes mellitus continues to increase worldwide, and it is a well-established cardiovascular risk factor. Hypertension is also an important cardiovascular risk factor to be controlled and is common among patients with diabetes mellitus. Optimal blood pressure (BP) goals have been the subject of great debate in …

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Bromocriptine-QR Therapy and its Impact on the Pro-inflammatory State of Type 2 Diabetes Subjects in Relation to CVD

Sponsored Content  Bromocriptine-QR (Cycloset) “is a sympatholytic dopamine D2 agonist for the treatment of type 2 diabetes that has demonstrated rapid (within 1 year) substantial reductions in adverse cardiovascular events in this population by as yet incompletely delineated mechanisms.” This study investigated the impact of Cycloset on the pro-inflammatory state …

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Finerenone improves cardiovascular outcomes in patients with Type 2 Diabetes and CKD

Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, improves cardiovascular events (MI, stroke, HF) in Type 2 Diabetes and Chronic Kidney Disease (CKD) patients.  Some risk factors for cardiovascular diseases (CVD), such as high blood glucose, blood pressure, serum cholesterol, and BMI, are also associated with CKD and type 2 diabetes. …

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Sickle Cell Disease and Diabetes Mellitus

Is there a link between patients living with sickle cell disease and diabetes mellitus? African-Americans/ Black are the most affected by sickle cell disease (SCD). According to the US Department of Health and Human Services Office of Minority Health, this population also has the highest prevalence of obesity. Sickle cell …

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Influence of Empagliflozin on Myocardial Flow Reserve in Patients With Type 2 Diabetes Mellitus

Sodium-glucose cotransporter 2 inhibitors lower the risk of hospitalization in heart failure and cardiovascular death…  The SIMPLE trial examined the effects of empagliflozin on myocardial flow reserve, showing microvascular perfusion in individuals with type 2 diabetes with high CVD risk. The SIMPLE trial is a single-center, double-blind, randomized clinical trial …

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DPP-4 Inhibitors Vs. Sulphonylureas As Add-On to Metformin – Assessing CV Outcomes in Type 2 Diabetes

New retrospective study results compare the two most largely prescribed antidiabetic medication classes in addition to metformin, to determine the impact on the incidence of CV events in patients with T2DM. Dipeptidyl-peptidase-4 inhibitors (DPP-4i) and sulphonylureas (sulfonylureas in the US) (SU) are two of the most prescribed medication to date …

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