Cardiology

Type 2 diabetes is associated with greater relative risk of CHD in women than in men, according to The British Regional Heart Study and British Women’s Heart Health Study.…

Diabetes patients are more susceptible to the development of atherosclerosis than non-diabetics and insulin therapy might help repair atherosclerotic lesions in diabetic patients….

GLP-1 receptors are widely expressed in CV, adipose, hepatic, and renal tissue. High-affinity GLP-1 receptors are present in autonomic nuclei that control CV functions, and have been isolated in rodent and human cardiomyocytes, endothelial cells, and vascular smooth muscle cells….

Glucagon-like peptide-1 mimetics improve certain cardiovascular risk factors, although it is unclear if the observed benefits are direct effects or indirect effects due to weight loss. Improvements in systolic blood pressure seen in exenatide and liraglutide trials are illustrated in Figure 3. The decreases in systolic blood pressure range from …