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SGLT2 Inhibitors and Beta-Cell Preservation

Phuong Nguyen, Doctor of Pharmacy Candidate, LECOM, College of Pharmacy Studies investigating both mice and humans have shown that chronic hyperglycemia may shift the balance of B-cell proliferation and apoptosis toward cell death, consequently resulting in B-cell deficiency and impaired insulin secretion. Idris and Donnelly (2009) studied the effect of …

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