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RESOURCES

Test Your Knowledge: Clinical Case Vignette: Smoking and Type 2

You are concerned about Mr. Carlson’s cigarette use because cigarette smoking has been shown to have multiple physiological impacts on health. Which one of the following statements regarding smoking and type 2 diabetes is true? A. It equally affects all-cause mortality in individuals with and without diabetes B. In individuals with diabetes, it causes more rapid progression to micro- and macroalbuminuria C. It has not been linked to worsening glycemic control D. The use of bupropion in contraindicated in diabetes Follow the link to see the answer,

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Combo Treatment to Reach Goal

Would you feel comfortable using a combination treatment of a GLP-1 receptor agonist and a SGLT-2 inhibitor for a patient who has not reached goal? Follow the link to respond.

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Don’t Stop: Encouraging Patient Success

When prescribed lifestyle changes and or medication(s), patients who have diabetes, obesity, hypertension, or any chronic condition that is easy to monitor, even from home, may agree to these changes at first. They can almost immediately get improvements in their numbers. It can be encouraging. For some, seeing those numbers change for the better encourages them to keep on keeping on. However, others may think they are healed and stop treatment. Their numbers may go back to the same or even "worse" than before the treatment.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #130: Pathogenesis of Type 2 Diabetes Mellitus Part 1

Normal glucose homeostasis: Any discussion of the pathogenesis of type 2 diabetes mellitus (T2DM) must start with a review of mechanisms involved in the maintenance of normal glucose homeostasis in the basal o postabsorptive state (10–12-h overnight fast) and following ingestion of a typical mixed meal. In the postabsorptive state the great majority of total body glucose disposal takes place in insulin independent tissues.

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