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Insulin’s contribution to obesity

Insulin itself may contribute to obesity. A high first-phase insulin response to intravenous glucose has been shown to be a risk factor for long-term weight gain, and this effect is particularly manifested in insulin-sensitive individuals. 76 Also, compared to normal children, Pima Indian children with elevated fasting insulin gain more …

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Diabetes and vascular disease — a single process?

Each hour, 178 people die from complications set off by diabetes. For 80 percent of these patients the killer is atherosclerosis involving the large blood vessels supplying heart and brain. Patients with diabetes are four times as likely as nondiabetic individuals to die of an MI. With endothelial dysfunction a …

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