Resources

Thiazolidinediones can cause or exacerbate heart failure and pulmonary oedema, and should be avoided in patients with left ventricular dysfunction or chronic renal insufficiency, according to the conclusion of a new report.

Significant reductions in life expectancy were also shown and the researchers estimate that if an individual “is diagnosed at age 40 years, men will lose 11.6 life-years…and women will lose 14.3 life-years.”

Cardiovascular complications are the leading cause of morbidity and mortality for people with diabetes; as many as 80% of patients with type 2 diabetes die from cardiovascular events.

An elevated glycemic load is an independent risk factor for future coronary events in patients with coronary heart disease (CHD), results of the Long-term Intervention with Pravastatin in Ischaemic Disease(LIPID) study. Reported at the 13th International Symposium on Atherosclerosis.

Novo Nordisk said on Wednesday it received an “approvable letter” from U.S. regulators for its new insulin product but analysts said it remains uncertain when the Danish firm will start selling the product.

Children who diet to control their weight may actually gain weight in the long run.

Simvastatin acts as a double therapeutic weapon by blocking the conversion of HMG-CoA to mevalonate. Not only does this action increase new bone formation via the stimulation of osteoblasts , but it also prevents the production of cholesterol.

Fasting plasma glucose and glycated hemoglobin concentrations normalized in 83% of patients and improved dramatically in 17%.

Excessive weight gain in patients with type I diabetes on intensive therapy may be associated with a family history of type 2 diabetes, according to a recent American study.

The assistance of a case manager decreases rates of hypoglycemia and hospitalization and associated costs (80,000/yr), and increases visit frequency in children with type 1 diabetes.