Resources

HLA-DR and -DQ: The highest risk of T1DM is conferred by heterozygosity for the DRB1*0301-DQA1*0501-DQB1*0201 and DRB1*04-DQA1* 0301-DQB1*0302 haplotypes, referred to as the DR3.DQ2/DR4.DQ8 genotype. This allelic combination is carried by 30–40% of individuals with T1DM, but only around 2.5% of the general population [3]. A recent meta-analysis of multiple ethnic groups suggested that this translates into an OR value greater than 16, an unusually large odds ratio for a complex disease [14]. This is consistent with an earlier study which estimated that the risk of developing T1DM was between 1 in 15 and 1 in 25 among those with the DR3.DQ2/DR4.DQ8 genotype, compared with 1 in 300 in the general population [15]. High risk is also conferred by the DR3.DQ2/DR3.DQ2 and DR4.DQ8/DR4.DQ8 homozygous genotypes (OR = 6.32 and OR = 5.68, respectively, from meta-analysis).

Which of the following items would you be interested in seeing added to DIC?

Optimism correlated with lower incidence of type 2 in postmenopausal women.

Major changes in weight, including weight loss, can affect diagnosis risk.

There is more going on than just the immune system attacking.

Use of albuminuria level changes as the endpoint to determine need to reduce albumin-to-creatinine ratio.

Is there a difference in glucose tolerance based on body weight and adipose tissue in type 2 diabetes?

Change in albuminuria as surrogate endpoint for progression of chronic kidney disease strongly supported by biological plausibility, but empirical evidence to support its validity in epidemiological studies lacking.

From 2002 to 2016, US deaths from chronic kidney disease (CKD) increased by how much?

A. 20%
B. 32%
C. 38%
D. 38%
E. 58%

Follow the link for the answer.

Which exercise equipment do you feel can be the most beneficial for those who have excess weight and who have diabetes or prediabetes?

- Treadmill
- Rowing Machine
- Elliptical Trainer
- Exercise Bike
- Weight Machine

Follow the link to share your opinion.