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When compared to insulin glargine, exenatide offered added benefits of weight loss and improved beta-cell function when used with metformin

“Imagine an inexpensive pill that could decrease the hemoglobin A1c value by 1 percentage point, reduce cardiovascular death by 25%, and substantially improve functional capacity (strength, endurance, and bone density),” Drs. Kraus and Levine write. “Diabetes experts would be quick to incorporate this pill into practice guidelines and performance measures …

A strategy of treating all diabetic men older than 40 years and all diabetic women older than 45 years with statins would be effective and efficient in reducing cardiovascular disease (CVD) events

In patients with type 2 diabetes, moderate daily intake of alcohol reduced fasting plasma glucose (FPG) but not postprandial glucose, especially in those with high levels of glycated hemoglobin.

Total activity — or more accurately, the lack of it — appears to be a major driver of insulin resistance, a key component of the metabolic syndrome and a cardiovascular risk factor.

Adding insulin to oral antidiabetic agents early in the course of disease can help patients achieve better glucose control, but many patients will need a combined insulin regimen, investigators reported.

Diamyd Medical announced last Thursday further evidence for lasting immunologic efficacy of the Diamyd® diabetes vaccine.and showed that treatment with Diamyd® causes a specific immune response to GAD65 remaining even 15 months after treatment.

Because most patients do not understand what an A1c result means, the industry standard will now be to tell patients what their average blood glucose is.

The American College of Physicians (ACP) has issued a guidance statement on the optimal hemoglobin A1c targets for patients with type 2 diabetes. More confusion?

Even in nondiabetics, increased HbA1c levels are associated with a significantly increased risk of nonfatal cardiovascular disease after other cardiovascular risk factors are accounted for.