By studying identical twins, researchers have identified mechanisms that could be behind the development of type 2 diabetes…. The study involved 14 pairs of identical twins in Sweden and Denmark. One of each twin had type 2 diabetes while the other was healthy. Emma Nilsson, the researcher who carried out …
Read More »Post-surgery Complications More Likely with Insulin-dependent Diabetes
Insulin-dependent diabetes patients were at an increased risk of post-surgery complications following lumbar fusion including death, sepsis, wound infection and 30-day readmission…. Patients with insulin-dependent diabetes mellitus (IDDM) have an increased risk of a number of postoperative complications after lumbar fusion compared with those who have noninsulin-dependent diabetes mellitus (NIDDM) …
Read More »Link between Lean BMI and Mortality in Diabetes
Type 2 diabetes patients with a BMI between 18.5 and 24.9 kg/m2 had the lowest mortality rate, while those in the 14.4 to 18.5 BMI range had an increased rate….
Read More »Tight Blood Sugar Control May Not Be Needed for Heart Bypass
Survival rates similar for those with looser glucose limits…. Some previous research has suggested that high blood sugar after bypass and other types of heart surgery was associated with increased risk of health problems and death, but more recent research has found that might not be the case. This new …
Read More »EASD: Insulin Pumps Lower Mortality Rate 29% Compared to Multiple Injections in T1DM
And fatal cardiovascular disease risk is 43% lower for type 1 diabetes patients using insulin pumps over multiple daily injections…. Dr. Gudbjörnsdottir and colleagues in Sweden conducted an observational study using patient data from the Swedish National Diabetes Registry from 1996 till 2014. The data included more than 95% of …
Read More »EASD: Targeting the Adaptive Glycosuria Response of SGLT2 Inhibitors Could Help Weight Loss
Combining SGLT2 inhibitor treatment with strategies to maintain energy intake or curb appetite could be an avenue for weight loss….
Read More »EASD: Probiotic Use and Islet Autoimmunity in Young Children
Early probiotic supplementation may reduce the risk of islet autoimmunity in young children…. Gut microbiota play an important role in enhancing immune system and excluding pathogens competition. Previous studies have shown that dysbiosis in gut microbiota and impaired gut barrier could be associated with type 1 diabetes in humans and …
Read More »EASD: Non-albuminuric CKD in Type 1 Diabetes Patients Increasing
Researchers are unsure why the phenotype is increasing but suggest that more effective treatments may be contributing to the increase in non-albuminuric CKD…. Chronic kidney disease (CKD) is a common complication of diabetes associated with glomerular filtration rate (GFR) loss. Normally, before the GFR loss occurs, albuminuria will be detected. …
Read More »EASD: Effects of Nitric Oxide on Insulin Clearance and Hepatic Lipid Metabolism
Higher levels of hypothalamic nitric oxide could lead to less insulin clearance and more lipogenesis…. Nitric oxide (NO) is an important neurotransmitter produced in the paraventricular nucleus (PVN) of the hypothalamus. Previous studies suggested that the level of NO was inversely correlated with systemic insulin clearance. However, little is known …
Read More »EASD: Diabetic Peripheral Neuropathy and the Risk of Falling on Stairs
Patients with diabetic peripheral neuropathy (DPN) are more likely to experience a fall during stair walking…. Diabetic peripheral neuropathy has been shown in previous studies to cause postural sway during standing and walking on level ground in diabetic patients but no data is available regarding the effect of DPN on …
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