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Two Gene Mutations Identified in Increased Risk of Obesity and Diabetes
Mutations in the ankyrin-B gene cause fat cells to soak up more glucose, setting the stage for obesity and insulin resistance… Ankyrin-B was discovered more than 30 years ago by researcher Vann Bennett at Duke University School of Medicine and the Howard Hughes Medical Institute. The gene plays a role …
Read More »Liver Disease Affects Metformin Metabolism
Increased diabetes drug exposure may increase risk of adverse reactions in type 2 patients with NASH… Obesity increases the risk of nonalcoholic steatohepatitis (NASH), which occurs when there is too much fat in the liver. NASH is often asymptomatic and because testing for it requires a liver biopsy, many cases …
Read More »Bromocriptine for High Dose Insulin Therapy Type 2 Patients
Treatment can decrease amount of total daily insulin dose due to insulin sensitizer properties… As the duration of diabetes diagnosis lengthens for patients, management of the disease gets more difficult. Insulin therapy is very effective in treating hyperglycemic events, however it carries unwanted side effects such as hypoglycemia and weight …
Read More »Diabetes Drug May Protect Against Parkinson’s Disease
Glitazone antidiabetes drugs found to decrease incidence of disease…
Read More »The Effectiveness of Combination Treatment with Insulin and Sitagliptin in T2 Patients
Patients on therapy may see increased reduction in HbA1c, lower BP, lower lipid values…. Dipeptidyl peptidase-4 (DPP-4) inhibitors are used for the treatment of type 2 diabetes. Sitagliptin was the first medication approved for people with type 2 diabetes who are taking insulin. There are not a lot of …
Read More »Impact of Exercise in Type 2 Diabetes Patients
Rise in cerebral blood flow studied as cause of fatigue during physical activity… The development of fatigue is still a complication among type 2 diabetics. During exercise, a person with diabetes will experience a loss of muscle generating capacity. Currently, the mechanism of action of reduced exercise tolerance is still …
Read More »The Outcome of DPP-4 Inhibitors in Type 2 Patients on Hemodialysis
Decreased chance of hypoglycemic event and greater safety profile shown in use of this therapy… Diabetes is the main reason for renal failure in today’s population. Currently, the main treatment option for a hemodialysis diabetic patient is insulin therapy. Insulin therapy is a difficult regimen for many patients due to …
Read More »Inhaled Formoterol May Be Useful in Preventing Hypoglycemia
Study finds that beta 2 adrenergic receptor (AR) agonist formoterol may prevent hypoglycemia by reducing the effect of insulin….
Read More »Telemonitoring of Diabetic Foot Ulcers Might Lead to More Death
Study finds higher mortality incidence in telemedical monitoring group compared with standard outpatient-monitoring group… Telemonitoring of diabetic foot ulcers involves remotely monitoring patients who are not at the same location as the health care provider. Patients communicate with a specialized ulcer nurse or physician at an outpatient clinic through telephone …
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