In this second set of a comprehensive four-part series of Homerun Slides on SGLT-2 inhibitors, we review some of the data of the second and third approved SGLT-2 inhibitors in the U.S., dapagliflozin (Farxiga) and empagliflozin (Jardiance), along with the Durability and Limitations of this drug class…. To download this …
Read More »Improving Outcomes with SGLT-2 Inhibitors in Challenging T2DM Patients, Part 1
In this first of a series of four sets of Homerun Slides, we review the basics of SGLT-2 inhibitors incuding Mode of Action, and Efficacy. and then look at how Canagliflozin has worked in poorly controlled type 2 diabetes patients…. To download the complete set in PowerPoint (.ppt) format, just …
Read More »Stanley Schwartz, MD: Classifying Diabetes Types, ADA 2014, Part 3
In this week’s Homerun Slides, Dr. Stanley Schwartz continues his exploration of a beta-cell centric classification model for diabetes and includes a detailed diagram explanation featuring the Egregious Eleven….
Read More »Stanley Schwartz, MD: Classifying Diabetes Types, ADA 2014, Part 2
In this week’s Homerun Slides set, we look at Dr. Stanley Schwartz’s presentation from this year’s ADA with his groundbreaking proposal to classify diabetes using a ‘Beta-cell Centric’ approach….
Read More »Autonomy Trial
The First Randomized Trial Comparing Two Patient-driven Approaches to Initiate and Titrate Prandial Insulin Lispro in Type 2 Diabetes In this Homerun Slides series, courtesy of Dr. Steven Edelman, on the AUTONOMY Trial we get an inside look at the groundbreaking results and conclusions that can be drawn from the patient driven …
Read More »Stanley Schwartz, MD: Classifying Diabetes Types, ADA 2014, Part 1
In this week’s Homerun Slides, we begin a series which Dr. Stanley Schwartz presented at the 2014 ADA Scientific Sessions, where he outlined some of the problems with the current diabetes classification system. This first section discusses the definition of LADA and shows how diabetes diagnosis characteristics frequently overlap….
Read More »Role of the Kidney, Part 10
In this week’s series of Homerun Slides, we take a more detailed look at the most recently approved SGLT2 inhibitor, dapagliflozin, and then explore some of the other SGLT2 inhibitors which are on the horizon….
Read More »Role of the Kidney, Part 9
In this week’s Homerun Slides, we covers topics including Familial Renal Glucosuria, Analysis of SGLT2 Gene in Patients with Renal Glucosuria, and the Effect of SGLT2 Inhibition on Renal Glucose Handling….
Read More »Role of the Kidney, Part 8
In this week’s Homerun Slides, we delve into the mechanisms of action of SGLT-2 Inhibitors and look at some of the studies involving animal models and what came out of those studies…. To download the complete set of this week’s slides, just use this link: Role of the Kidney, Part 8 …
Read More »Role of the Kidneys, Part 7
In this week’s Homerun Slides, we delve further into the pathophysiology and treatment of type 2 diabetes covering topics including: altered Hypothalamic Function in Response to Glucose Ingestion in Obese Humans; the UKPDS trial – Effect of Glibenclamide and Metformin Therapy on HbA1c; and the ADOPT trial – Effect …
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