July 6, 2019 : Issue #997

TOP STORIES — Diabetes News and Research

The ASCEND Study – Aspirin for Prevention of Cardiovascular Events

The Risks of Cognitive Impairment in Our Elderly Patients with Diabetes

Cardiovascular Benefits of Oral GLP-1RA in High-Risk Patients with Type 2 Diabetes

Debunking Some Physical Activity and Training Myths

by Sheri R. Colberg, PhD, FACSM

I recently gave up my cable TV and DVR, and in order to get network channels I put a paper-thin HD antenna on my window to get them for free.

The downside is that I sometimes have to watch commercials.

I know that January is when all the fitness experts are selling their programs, but I guess they are back again to get all of us beach ready. This week our fitness expert Dr. Sheri Colberg looks at these programs and shares her “favorite” exercise myths with you. This might just be worth printing and handing out in the waiting room.

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We can make a difference!

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Dave Joffe

Editor-in-chief

The study findings demonstrate a balance between cardiovascular protection and major bleeding. 

How does diabetes affect the risk of developing late-life mild cognitive impairment or dementia?  

Results from the recently published PIONEER trial series demonstrate the overall diabetic benefits of oral semaglutide, a novel GLP-1 receptor agonist. 

How often have you heard things about physical activity and exercise training that you thought sounded correct, but found out later they were totally wrong? If you hang out at a gym or even talk with training coaches, you’ll hear about everything, including contradictory statements about how to be active the right way. Should you work out in a “fat burning” range? Is weight training going to make you bulk up? Will your muscles turn to fat if you stop working out? Do you need to eat a lot more protein to get bigger muscles? Confused? Here is the truth about some of the more common myths you’ll hear about being active.

Family background can matter for the health of children with diabetes, according to researchers,  who found young patients’ blood sugar control was linked with the level of education their mothers had attained. To examine inequality in glycemic control by maternal educational level among children with type 1 diabetes in a setting with universal access to health care, they did a longitudinal nationwide study of 4,079 children with type 1 diabetes between the years 2000 and 2013. Children were divided into four groups based on mothers’ education pre-birth (≤high school [n = 1,643], vocational or 2-year college [n = 1,548], bachelor’s degree [n = 695], ≥master’s degree [n = 193]). Means of socioeconomic and treatment characteristics were compared between groups. HbA1c and the number of daily glucose tests were compared repeatedly from onset until 5 years after onset across groups. HbA1c was compared across daily blood glucose testing frequency and groups. Linear regression was used to compare HbA1c across groups with and without adjustment for socioeconomic and treatment characteristics. In the current study, HbA1c levels averaged 7.6% in children of mothers with advanced degrees, 7.9% in children of women with bachelor’s degrees, 8.2% in children whose mothers graduated from vocational or 2-year colleges, and 8.4% in children of mothers with no more than a high school degree. Children of better-educated mothers also had lower rates of a dangerous condition known as diabetic ketoacidosis, and lower rates of dangerously low blood sugar that can result from overdoses of insulin. Differences in how often kids’ blood sugar levels were checked during the day likely explained a large part of the disparities, the authors say.  Children of the most highly educated mothers had the highest number of daily blood glucose tests, while those of mothers with a high school education or less had the lowest. Other potential explanations, the authors write, are that mothers with higher education may be more capable of helping manage diabetes and could help their kids on how to control their disease. Still, the researchers write in Diabetes Care, “For clinicians and policymakers, our results suggest that it may be beneficial to provide extra support to the least privileged children during the first few years of diabetes.”   Diabetes Care

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:

Marian Ayad, BPharm, PharmD candidate, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Adam Chalela, B.S., Doctor of Pharmacy Candidate, Class of 2020, USF College of Pharmacy

Emma Kammerer, PharmD Candidate, Class of 2020, L|E|C|O|M Bradenton School of Pharmacy

Maya Rudolph, PharmD Candidate, Florida A&M University College of Pharmacy & Pharmaceutical Sciences

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