February 21, 2017 : DCMS #333

DISASTERS AVERTED — Near Miss Case Studies

Sugar Free, Gluten Free, And Vegan Are NOT Carb Free

EXCLUSIVE INTERVIEW — Candid Video Interviews with Top Practitioners

Blandine Lacroix Part 1, Understanding Obesity the Disease

HOMERUN SLIDES — Great Clinical Presentation Highlights

SGLT-2 Part 2

CLINICAL GEMS — The Best from Diabetes Texts

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #63: Mechanisms of Insulin Signal Transduction Part 7 of 8

MOST POPULAR ARTICLES OF THE MONTH

#1 Caution: NSAIDs with SGLT-2 Inhibitors May Cause Renal Injuries
#2 CGM Will Change The Way We Treat Type 1 And Type 2 Diabetes
#3 New ADA 2017 Standards of Medical Care in Diabetes

We have this great Mexican restaurant that opened a few months ago in South St. Petersburg. The food is fantastic, and the service is amazing; however, because the whole family eats lower carb, we don’t go there as often as we would like. About two months ago, my wife asked Louie, the owner, if he would use low carb wraps if we brought them. He was happy to accommodate us, and it has worked out perfectly. He even fries the wraps to make us chips to dip in their fabulous salsa.

Friday when we came in, Louie had a big smile on his face and proudly announced that he had gotten us gluten-free wraps so we did not need to bring ours anymore. It is amazing how some people interpret foods. To see how those misconceptions can be harmful, check out this week’s Disaster Averted.

In case you missed it: dMeetings is a new way to educate your diabetes patients that gives them the freedom to learn at their own pace from knowledgeable certified educators.To learn how to get started with dMeetings, see our recent New Product item.

Dave Joffe

Editor-in-chief

Woman, 53 years of age. Type 2 diabetes and is obese. Patient’s daughter was getting married. She was very motivated to lose weight for the wedding and she did. Her A1C lowered from 7.5% to 6.6%. She cut back on her carbs to <100gm/day, increased her activity and took her metformin regularly. She lost 22 pounds over 6 months. The wedding was 2 months ago and she has gained 6 pounds. That may not seem like much, but it was enough to raise her A1C and open her eyes.

Blandine Lacroix talks with Diabetes in Control Publisher Steve Freed at the 2016 AACE Meeting. In part 1 of this Exclusive Interview, Blandine Lacroix explains the focus of Novo Nordisk on understanding how to improve the care of obesity in the search for the cure for diabetes.

In this week’s Homerun Slides, the safety warnings, precautions, and incorporation of SGLT-2 inhibitors into diabetes treatment.

Insulin resistance in humans: abnormalities in insulin signaling and in the glucose transport effector system
Although the key elements of the insulin signaling network have been defined by studies employing molecular and cell biology techniques, a number of studies have focused on translating this knowledge to human studies in a clinical research setting. Insulin resistance in peripheral tissues characterizes obesity and T2DM, and is involved in the pathogenesis of diabetes.

New research finds issue in the setting of dehydration and/or during use of nonsteroidal anti-inflammatory agents (NSAIDs) or radiocontrast studies.

Let’s start off with what is in the pipeline.

Psychological health, access to care, expanded and personalized treatment options and the tracking of hypoglycemia emphasized.