Exubera Patients to Transition to Technosphere Inhaled Insulin

MannKind Corporation and Pfizer announced that MannKind will transition certain Exubera patients with a continuing need for inhaled insulin to MannKind’s inhaled insulin product, Technosphere(R) Insulin. Technosphere Insulin is an investigational product that has recently completed Phase 3 clinical trials. In October 2007, Pfizer announced that it would stop marketing Exubera (insulin human (rDNA origin)) Inhalation Powder because it did not meet customers’ needs or Pfizer’s financial expectations. Since that time, Exubera patients have been transitioning to other diabetes therapies, although there remains a small number of patients with a continuing medical need for inhaled insulin. Pfizer began discussions with MannKind to give these patients access to Technosphere Insulin. Pfizer will reimburse some of MannKind’s costs relating to the transition of patients.

According to MannKind’s Chief Scientific Officer, Dr. Peter Richardson, "For some Exubera patients, continued treatment with inhaled insulin is needed. These patients generally fall into two categories: those with severe needle-phobia or a very poor response to subcutaneous insulin. This small number of patients represents a group with particularly high medical need who will benefit from using an inhaled insulin such as Technosphere Insulin."

MannKind Corporation’s inhaled insulin called Technosphere Insulin, has completed Phase 3 clinical trials

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