Surgery

Blood glucose showed significant decrease months after procedure… Type 2 diabetes has become more common in today’s society. Currently, modified gastric bypass surgery is used to treat type 2 diabetes. This intervention has been utilized since the 1990s. The procedure reached 83% efficiency and currently the therapeutic mechanism is still …

Oxidized LDL (oxLDL) cholesterol and fructosamine are associated with severe heart disease in women…. Insulin resistance is known to increase risk for cardiovascular diseases. However some patients with insulin resistance appear to experience only moderate symptoms of coronary blockage while others suffer severe coronary atherosclerotic and continue to progress after …

Current weight management programmes focused on dieting and exercise may not be effective in tackling obesity at population level…. The chance of an obese person attaining normal body weight is 1 in 210 for men and 1 in 124 for women, increasing to 1 in 1,290 for men and 1 …

This week we are excited about our exclusive interview with Dr. Janice Smiell, CMO at Alliqua BioMedical, Inc. Dr. Smiell and her team have been doing some groundbreaking work on battling chronic wounds using placental biomaterials. Steve Freed:  Welcome, Dr. Janice Smiell. Let’s begin by having you tell us a …

Results from a three-year study show surgical intervention is superior to intensive lifestyle intervention in achieving meaningful, lasting glycemic control in type 2 diabetes… A study conducted at the University of Pittsburgh Medical Center beginning in October 2009 and concluding in June of 2014 randomized 61 obese patients (BMIs ranged …

A protein encoded by the gene glypican-1 (GPC1) present on cancer exosomes may be used as part of a potential non-invasive diagnostic and screening tool to detect early pancreatic cancer….

David Levy, MD, FRCP      Erectile dysfunction This is the commonest neuropathic complication: 20% of men have erectile dysfunction (ED) at diagnosis, increasing to 34% at 12 years (UKPDS). The prevalence in a newly diagnosed Kuwaiti population was 30%, and nearly 50% in a large survey of Canadians attending their primary-care physicians …

David Levy, MD, FRCP      Mononeuropathies and other focal syndromes Peripheral mononeuropathies Upper limb Carpal tunnel syndrome (median nerve) Carpal tunnel syndrome is very common (remember the association with primary hypothyroidism, especially in type 1 diabetes) and may present with atypical symptoms, as it is often superimposed on diabetic polyneuropathy. Consider it …

David Levy, MD, FRCP      Charcot neuroarthropathy Charcot neuroarthropathy is a serious and poorly understood condition associated with rapid destruction of bones and joints and resulting in bone fragmentation. It occurs only in patients with advanced sensory and autonomic neuropathy, and is characteristic of long-duration type 1 diabetes with other microvascular complications, …

David Levy, MD, FRCP      Foot ulceration The ulcerated, infected and possibly gangrenous foot is a common reason for hospital admission. Anatomically, diabetic foot ulceration is restricted to the region distal to the ankle; proximal lesions are more likely ischemic, vasculitic, venous, or to have another underlying cause. Most ulcers are predominantly …