Sulfonylurea

Diabetes Solution Richard K. Bernstein, MD, FACE, FACN, FACCWS Part 2 Chapter 22 Gastroparesis How Does Gastroparesis Affect Blood Sugar Control? – Part 2Consider the individual who has very little phase I insulin release and must take fast-acting insulin or one of the older-type (sulfonylurea) or newer pancreas-provoking OHAs before …

In this week's Homerun Slides, we see how sulfonylureas, metformin and TZDs work in the treatment type 2 diabetes...

Researchers study antidiabetic treatments, other factors associated with control… There are two main kidney diseases that are correlated with type 2 diabetes, which are chronic kidney disease and diabetes nephropathy. Good glycemic control can interrupt the progression of kidney diseases in type 2 diabetes patients with renal problems. Currently, the …

A 59 YOF is recently discharged from hospital after an allergic reaction to an anesthesia induction agent. She was placed on high-dose steroid for the reaction while she was in the hospital. Patient had completed her steroid tapering dose 2 months prior to her visit to endocrinology clinic today due to high blood glucose (a1c 8.9%). Past medical history included: hypertension, hyperlipidemia, atrial fibrillation, obesity and diabetes for 7 years. She was well controlled on metformin 1000mg BID before...

Low glucose events requiring emergency services differs according to diabetes type… Hypoglycemic episodes are a common event among patients with diabetes. Most hypoglycemic events are treated without ambulance services or admission to a hospital. However, severe hypoglycemic events are treated differently. Severe hypoglycemia is defined as “an episode requiring external …

The way that type 2 diabetics respond to initial treatment could predict the long term effectiveness of their treatment regimen… There are a variety of treatment options for type 2 diabetics, with no clear reason why some drugs work better than others in some individuals. That is why diabetes treatment …

GLP-1 agonists have additional benefits for type 2 diabetes besides lower blood glucose… Over 1.4 billion adults were overweight in 2008, and of the 1.4 billion people, 500 million were obese. Obesity is defined as a body mass index >30 g/m2. Also, obesity increases the chance of being diagnosed with …

In the study, sulfonylureas correlated with a significant increase in levels of free fatty acids….

Drug shows a significant reduction in HbA1c in patients with type 2 diabetes… A new investigational drug is underway to help with reduction of HbA1c, weight, and improve glycemic control in type 2 diabetes patients. ITCA 650 is an injection-free GLP-1 receptor agonist that provides continuous subcutaneous exenatide for 12 …

Sulfonylureas not associated with increased cardiovascular mortality, myocardial infarction and stroke in a meta-analysis of 47 randomized clinical trials… Sulfonylureas are relatively inexpensive and are important therapeutic agents in type 2 diabetes management. However, they are not widely used due to safety concerns regarding hypoglycemia and weight gain. Furthermore, it …