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Dace Trence Part 4, New Trials and Breakthroughs for Diabetes

In part 4 of this Exclusive Interview, Dace Trence talks with Diabetes in Control during the AACE 2018 convention in Boston about the latest treatments and possible treatment breakthroughs for diabetes.

Dace Trence MD, FACE is the Director of the Endocrine and Diabetes Care Center at the University of Washington in Seattle.


Transcript of this video segment, Dace Trence Part 4, New Trials and Breakthroughs for Diabetes:

Freed: And what do you think the next biggest breakthrough is going to be in the field of diabetes and cardiovascular disease?

Trence: Well, you added cardiovascular disease. If you told me just diabetes alone, I would certainly say the movement towards having the synchrony between a sensor and an insulin delivery device. So, that really takes you, the person, out of the decision making process. Certainly we have one such system now that has come out very recently, but I think we’re going to see more and more of these where that really kind of takes over. And perhaps even to the point that you may have a sensor on the dashboard of the car, so that you’re watching your blood sugar as you’re driving. Heaven forbid, not consistently watching it but it’s there recording or at least giving you a signal if it’s wrong or something is going awry. So, I think technology is going to increasingly address the issue of spontaneity, knowing what to do. Also, we’ll have a better idea of what should our targets really be. I mean, if we’re really still thinking that blood sugars are related to cardiovascular disease, and I think we still have some thought not totally band-aiding that, what is it about the blood sugar that it’s critical? Is it the certain level? Is it less variability or is it both? I mean, do you have to achieve a certain level with a certain degree of lower variability to really be able to impact on cardiovascular disease?

Freed: And coming up, the ADA, is there anything that you think that is going to be important coming out of this year’s meeting?

Trence: Everything.

Freed: Nothing in particular?

Trence: Well, I think we’re hoping that there’ll be some studies reported that will give us some more insight in to drugs that can give us additional cardiovascular benefit. I think there’s a lot of movement in that direction, so I think that will be very helpful. We’re certainly looking at the tools that we do have already. Perhaps looking at some of the older tools that we’ve had and thought that, “Well, maybe we should abandon them.” The old insulins, unfortunately have one big benefit and that is, it’s less cost. You don’t necessarily need to have a prescription to get a few of these. How do you make them work in the era where people are a little strapped for money?

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