Type 2 Diabetes

How do the effectiveness and safety of long-acting GLP-1 RAs compare to short-acting GLP-1 RAs, when paired with basal insulin? 

Study identifies multiple risk factors for type 2 diabetes, including insomnia, that need to be incorporated into diabetes prevention strategies.

Whole fruits, but not fruit juice, sustain insulin sensitivity and lessen the risk of type 2 diabetes.

Approximately 30% to 53% of diabetes mellitus cases in the United States can be attributed to obesity. 

HbA1c variability and swings between hypo- and hyperglycemia can increase risk of developing cardiovascular disease.

SURPASS-4 is a randomized controlled trial of tirzepatide once a week vs. insulin glargine once a day in type 2 diabetes patients with high cardiovascular risk.

Study finds incidence of type 2 diabetes reduced by 32% in participants taking dapagliflozin vs. placebo. 

A recently published study suggests that supplementation with select strains of naturally occurring gut bacteria may improve postprandial glucose control in patients with T2DM.

Central adiposity shows varying effects on blood pressure, LDL cholesterol, and glycemic profile. 

Novel dual GIP and GLP-1 receptor agonist showed promising results for both reduction in A1C and weight loss.