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ADA 2021: Finerenone in the Chronic Kidney Disease and Diabetes Population

Aug 10, 2021
 
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Alan Martinez, PharmD Candidate, University of South Florida Taneja College of Pharmacy

Finerenone is a mineralocorticoid receptor antagonist indicated for chronic kidney disease (CKD) with type 2 diabetes. Does the use of insulin affect its performance against kidney and cardiovascular issues?

The Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease (FIDELIO-DKD) study showed that finerenone reduces kidney and cardiovascular complications in patients with CKD and type 2 diabetes. In addition, the results demonstrated consistency independent of insulin use at baseline, and this area is the main focus of this subgroup analysis. The purpose of this analysis is to determine the amount of influence that insulin use has on kidney and cardiovascular outcomes and safety....

 

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